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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/haematology/myeloproliferative-neoplasms/essential-thrombocythaemia
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Myeloproliferative neoplasms / Essential thrombocythaemia
4
trial(s) found.
NCT07623200
Haem
Phase 3
Recruiting
A Phase 3, Randomized, Open-Label Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia and a CALR Mutation Previously Treated With Cytoreductive Therapy (
EXCALIBUR-ET2
)
anti-CALR monoclonal antibody
Essential thrombocythaemia
NSW
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
2170 - Liverpool - Liverpool Hospital
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3128 - Box Hill - Box Hill Hospital - Eastern Health
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4575 - Birtinya - Sunshine Coast University Hospital
WA
6000 - Perth - Royal Perth Hospital
6168 - Cooloongup - Rockingham Hospital
NCT07612280
Haem
Phase 1 / Phase 2
Recruiting
Study to Assess Safety and Preliminary Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis (
JBI-802-102
)
LSD1/HDAC6 inhibitor
Essential thrombocythaemia
Myelodysplastic syndrome
Myelodysplastic/Myeloproliferative disease
Myeloproliferative Neoplasm
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2109 - North Ryde - Macquarie University Hospital
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
3168 - Clayton - Monash Medical Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6005 - West Perth - Perth Blood Institute
6009 - Nedlands - Hollywood Private Hospital
NCT07469891
Haem
Phase 1
Recruiting
A Phase 1, Open-Label, Multi-Center, Safety and Efficacy Study of PRT12396 in Participants With Polycythemia Vera and Myelofibrosis (
PRT12396-01
)
JAK2 inhibitor,JH2 domain selective
Essential thrombocythaemia
Myelofibrosis
Myeloproliferative Neoplasm
Polycythemia vera
VIC
3168 - Clayton - Monash Medical Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6009 - Nedlands - One Clinical Research
NCT07357727
Haem
Phase 3
Recruiting
A Phase 3, Randomized, Double-blind, Active-control Study of Pelabresib (DAK539) and Ruxolitinib vs. Placebo and Ruxolitinib in Adult Patients With Myelofibrosis Who Are JAK Inhibitor Naive (
MANIFEST-3
)
BET inhibitor
JAK1/JAK2 inhibitor
placebo
Essential thrombocythaemia
Myelofibrosis
Polycythaemia vera
VIC
3168 - Clayton - Monash Medical Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
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Recruitment Status
Recruiting (4)
Recruitment Country and State
VIC (4)
WA (3)
SA (3)
NSW (2)
ACT (1)
QLD (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (1)
Phase 3 (2)
Trial Type
Haem (4)
Cancer Therapy Class
CALR
25%
HDAC6
25%
LSD1
25%
BET
25%
JAK1
25%
JAK2
25%
Facility
3168 - Clayton - Monash Medical Centre (3)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (3)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
2170 - Liverpool - Liverpool Hospital (1)
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital (1)
2605 - Garran - The Canberra Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
4575 - Birtinya - Sunshine Coast University Hospital (1)
6000 - Perth - Royal Perth Hospital (1)
6168 - Cooloongup - Rockingham Hospital (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2109 - North Ryde - Macquarie University Hospital (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
6005 - West Perth - Perth Blood Institute (1)
6009 - Nedlands - Hollywood Private Hospital (1)
6009 - Nedlands - One Clinical Research (1)
Cancer Type
Cancer
Essential thrombocythaemia
Haematological malignancy
Myeloproliferative neoplasm
Myelofibrosis
Polycythaemia vera
Myelodysplastic syndrome
Myelodysplastic/Myeloproliferative disease
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