ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/breast/adjuvant-neoadjuvant
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Breast / Breast - Adjuvant/neoadjuvant
14
trial(s) found.
NCT07527819
Curative
Not yet recruiting
Evaluating Ovarian Toxicity Outcomes Following Immunotherapy in Patients With Triple-Negative Breast Cancer (TNBC) (
FERTILE
)
Triple-negative breast cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2060 - North Sydney - Mater Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
SA
5112 - Elizabeth Vale - Lyell McEwin Hospital
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - ICON Cancer Care Hobart
NCT06966700
Curative
Phase 3
Recruiting
A Phase 3, Randomized, Open-label Study to Evaluate the Efficacy and Safety of Sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer (
2870-032
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
platinum-based antineoplastic agent
taxane
Breast cancer
HER2-negative breast cancer
Triple-negative breast cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2109 - North Ryde - Macquarie University Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3168 - Clayton - Monash Medical Centre
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.6035 - Wellington - Bowen Hospital
NCT06492616
Curative
Phase 3
Recruiting
Elacestrant Versus Standard Endocrine Therapy in Women and Men With Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast Cancer With High Risk of Recurrence-A Global, Multicenter, Randomized, Open-label Phase 3 Study (
ELEGANT
)
selective estrogen receptor degrader
Breast cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2060 - North Sydney - Mater Hospital
2109 - North Ryde - Macquarie University Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2217 - Kogarah - St George Hospital
2290 - Gateshead - Genesis Cancer Care, Lake Macquarie Private Hospital
2444 - Port Macquarie - Mid North Coast Cancer Institute-Port Macquarie Base Hospital
2480 - Lismore - Lismore Base Hospital
VIC
3066 - Epping - Northern Hospital
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3128 - Box Hill - Box Hill Hospital - Eastern Health
3135 - Ringwood East - Maroondah Hospital
3168 - Clayton - Monash Medical Centre
3630 - Shepparton - Goulburn Valley Health
QLD
4066 - Auchenflower - Icon Cancer Centre at Wesley Hospital
4215 - Southport - ICON Cancer Care
4812 - Hyde Park - Icon Cancer Centre Townsville
SA
5000 - Adelaide - Cancer Research SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5011 - Woodville South - The Queen Elizabeth Hospital
5037 - Kurralta Park - Icon Cancer Centre Adelaide
5042 - Bedford Park - Flinders Medical Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - ICON Cancer Care Hobart
7250 - Launceston - Launceston General Hospital - Northern Cancer Centre
NCT06393374
Curative
Phase 3
Recruiting
A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery (
2870-012
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Triple-negative breast cancer
NSW
2109 - North Ryde - Macquarie University Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3199 - Frankston - Peninsula Health Frankston Hospital
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT05866458
Curative
Recruiting
Radiation OmisSion in PAtients With CLinically Node Negative Breast Cancer Undergoing Lumpectomy and With a PathologIc Complete REsponse After Neoadjuvant Chemotherapy (
ROSALIE
)
Breast cancer
NSW
2031 - Randwick - Prince of Wales Hospital
2060 - North Sydney - Mater Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2170 - Liverpool - Liverpool Hospital
2487 - Cudgen - Tweed Valley Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3002 - East Melbourne - Victoria Breast & Oncology Care
3065 - Fitzroy - St Vincent's Hospital Melbourne
3128 - Box Hill - Box Hill Hospital - Eastern Health
3165 - Bentleigh East - Monash Medical Centre - Moorabbin
3844 - Traralgon - Latrobe Regional Hospital
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6000 - Perth - Royal Perth Hospital
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
NCT05827081
Curative
Phase 3
Recruiting
A Phase IIIb Study to Characterize the Efficacy and Safety of Adjuvant Ribociclib Plus Endocrine Therapy in a Close-to-clinical Practice Patient Population With HR+ HER2- Early Breast Cancer (Adjuvant WIDER) (
Adjuvant-WIDER
)
CDK4/6 inhibitor
Breast cancer
NT
0810 - Tiwi, Royal Darwin Hospital - Northern Centre for Oncology
NSW
2290 - Gateshead - Genesis Cancer Care, Lake Macquarie Private Hospital
VIC
3002 - East Melbourne - Epworth Freemasons
3168 - Clayton - Monash Medical Centre
NCT05774951
Curative
Phase 3
Recruiting
CAMBRIA-1
: A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy With Camizestrant (AZD9833, a Next Generation, Oral Selective Estrogen Receptor Degrader) Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) in Patients With ER+/HER2- Early Breast Cancer and an Intermediate or High Risk of Recurrence Who Have Completed Definitive Locoregional Therapy and at Least 2 Years of Standard Adjuvant Endocrine-Based Therapy Without Disease Recurrence
selective estrogen receptor degrader
selective estrogen receptor modulator
Breast cancer
NSW
2031 - Randwick - Prince of Wales Hospital
2139 - Concord - Concord Repatriation General Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
2485 - Tweed Heads - The Tweed Hospital (WITHDRAWN)
VIC
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit
QLD
4575 - Birtinya - Sunshine Coast University Hospital
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (WITHDRAWN)
NCT05633654
Curative
Phase 3
Recruiting
A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (
GS-US-595-6184
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Triple-negative breast cancer
NSW
2290 - Gateshead - Genesis Cancer Care, Lake Macquarie Private Hospital
2444 - Port Macquarie - Mid North Coast Cancer Institute-Port Macquarie Base Hospital
2560 - Campbelltown - Macarthur Cancer Therapy Centre - Campbelltown Hospital
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (WITHDRAWN)
VIC
3168 - Clayton - Monash Medical Centre
3550 - Bendigo - Bendigo Health - Bendigo Cancer Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4812 - Townsville - Townsville University Hospital
4870 - Cairns - Cairns Base Hospital
SA
5000 - Adelaide - Cancer Research SA
WA
6150 - Murdoch - Fiona Stanley Hospital
ACTRN12626000573358
Curative
Not Applicable
Not yet recruiting
Evaluating the impact of a nurse-led clinic model of care on the symptom management of women prescribed adjuvant endocrine therapy for early breast cancer: a quasi-experimental pilot study
Breast cancer
ACTRN12625001091493
Curative
Not Applicable
Recruiting
The
FERTILE
Study: Evaluating ovarian toxicity outcomes following immunotherapy in patients with Triple-Negative Breast Cancer (TNBC)
Breast cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2060 - North Sydney - Mater Hospital
VIC
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
SA
5112 - Elizabeth Vale - Lyell McEwin Hospital
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - Royal Hobart Hospital
ACTRN12623000657628
Curative
Phase 2
Recruiting
BCT 2301 (
OLIO
): A phase II, randomised, non-comparative two-arm trial of neoadjuvant chemotherapy plus either olaparib or olaparib + durvalumab in young, pre-menopausal women with HR-positive, HER2-negative early breast cancer
PARP1/2 inhibitor
anti-PD-L1 monoclonal antibody
Breast cancer
ACTRN12609000504213
Curative
Not Applicable
Recruiting
Cardiac monitoring with echocardiogram and tissue doppler imaging (TDI) and serum biomarkers to assess for cardiotoxicity with anthracyclines in women during adjuvant chemotherapy for breast cancer. (
ECHO
)
Cyclophosphamide
Docetaxel
Fluorouracil
alkylating agent
antimetabolite
cancer therapy
cytotoxic chemotherapy
fluoropyrimidine
taxane
Breast cancer
ACTRN12606000030572
Curative
Phase 2
Recruiting
An open label phase 2 study of doxorubicin and cyclophosphamide followed by paclitaxel (AC-T) delivered every 14 days with pegfilgrastim and darbepoetin alfa support for the adjuvant treatment of women with breast cancer (
ACCELERATE
)
alkylating agent
anthracycline
erythropoiesis stimulating agent
granulocyte colony stimulating factor
taxane
Breast cancer
ACTRN12605000732684
Curative
Not Applicable
Not yet recruiting
Analysis of angiogenesis markers, circulating tumour, endothelial progenitor, endothelial, dendritic, T and B cells in women receiving adjuvant chemotherapy for early breast cancer.
Breast cancer
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Recruitment Status
Recruiting (11)
Not yet recruiting (3)
Recruitment Country and State
NSW (9)
VIC (9)
WA (6)
QLD (5)
SA (4)
TAS (3)
NZ (1)
NT (1)
Phase
Phase 2 (2)
Phase 3 (6)
Trial Type
Curative (14)
Cancer Therapy Class
PD-1/PD-L1
29%
PD-1
21%
Trop2
21%
oestrogen axis
21%
PARP
14%
ER
14%
CDK4
7%
CDK6
7%
GnRH
7%
androgen axis
7%
PD-L1
7%
Facility
3168 - Clayton - Monash Medical Centre (6)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (5)
2060 - North Sydney - Mater Hospital (4)
3128 - Box Hill - Box Hill Hospital - Eastern Health (4)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (4)
2050 - Camperdown - Chris O'Brien Lifehouse (3)
2109 - North Ryde - Macquarie University Hospital (3)
2290 - Gateshead - Genesis Cancer Care, Lake Macquarie Private Hospital (3)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
5112 - Elizabeth Vale - Lyell McEwin Hospital (2)
7000 - Hobart - ICON Cancer Care Hobart (2)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (2)
2444 - Port Macquarie - Mid North Coast Cancer Institute-Port Macquarie Base Hospital (2)
5000 - Adelaide - Cancer Research SA (2)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (2)
2031 - Randwick - Prince of Wales Hospital (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
NZ.6035 - Wellington - Bowen Hospital (1)
2217 - Kogarah - St George Hospital (1)
2480 - Lismore - Lismore Base Hospital (1)
3066 - Epping - Northern Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3135 - Ringwood East - Maroondah Hospital (1)
3630 - Shepparton - Goulburn Valley Health (1)
4066 - Auchenflower - Icon Cancer Centre at Wesley Hospital (1)
4215 - Southport - ICON Cancer Care (1)
4812 - Hyde Park - Icon Cancer Centre Townsville (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
5037 - Kurralta Park - Icon Cancer Centre Adelaide (1)
5042 - Bedford Park - Flinders Medical Centre (1)
7250 - Launceston - Launceston General Hospital - Northern Cancer Centre (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
2170 - Liverpool - Liverpool Hospital (1)
2487 - Cudgen - Tweed Valley Hospital (1)
3002 - East Melbourne - Victoria Breast & Oncology Care (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
3165 - Bentleigh East - Monash Medical Centre - Moorabbin (1)
3844 - Traralgon - Latrobe Regional Hospital (1)
6000 - Perth - Royal Perth Hospital (1)
0810 - Tiwi, Royal Darwin Hospital - Northern Centre for Oncology (1)
3002 - East Melbourne - Epworth Freemasons (1)
2139 - Concord - Concord Repatriation General Hospital (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2485 - Tweed Heads - The Tweed Hospital (1)
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit (1)
4575 - Birtinya - Sunshine Coast University Hospital (1)
2560 - Campbelltown - Macarthur Cancer Therapy Centre - Campbelltown Hospital (1)
3550 - Bendigo - Bendigo Health - Bendigo Cancer Centre (1)
4812 - Townsville - Townsville University Hospital (1)
4870 - Cairns - Cairns Base Hospital (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
7000 - Hobart - Royal Hobart Hospital (1)
Cancer Type
Breast cancer
Cancer
Solid tumour
Breast adenocarcinoma
Triple-negative breast cancer
HER2-negative breast cancer
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