ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/breast/metastatic/triple-negative/first-line
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Breast / Breast - Metastatic / Triple negative / First line
4
trial(s) found.
NCT07173751
Advanced
Phase 3
Recruiting
A Phase III, Multisite, Randomized, Double-Blind Trial of BNT327 in Combination With Chemotherapy Versus Placebo With Chemotherapy in Patients With Previously
Untreated
Locally Recurrent Inoperable or Metastatic
TNBC
Determined Ineligible for PD(L)1 Therapy Based on PD-L1 Negative Disease (
BNT327-05
)
bispecific PD-L1/VEGFA antibody
placebo
Breast cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3168 - Clayton - Monash Children's Hospital
3199 - Frankston - Peninsula Health Frankston Hospital
SA
5000 - South Australia - GenesisCare St Andrews Hospital
NCT06926868
Advanced
Phase 2 / Phase 3
Recruiting
IZABRIGHT-Breast01: A Randomized, Open-label, Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) Versus Treatment of Physician's Choice in Patients With Previously
Untreated
, Locally Advanced, Recurrent Inoperable, or Metastatic
Triple-negative
Breast Cancer (
TNBC
) or ER-low, HER2-negative BC Who Are Ineligible for Anti-PD1/PD-L1 Treatment (
CA244-0008
)
bispecific EGFR/ERBB3 antibody
Breast cancer
Triple-negative breast cancer
NSW
2109 - North Ryde - Macquarie University Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
NCT06841354
Advanced
Phase 3
Recruiting
A Phase 3, Randomized, Open-label Study Comparing Efficacy and Safety of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as a Monotherapy and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With Previously
Untreated
Locally Recurrent Unresectable or Metastatic
Triple-Negative
Breast Cancer Expressing PD-L1 at CPS Less Than 10 (TroFuse-011) (
2870-011
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Triple-negative breast cancer
NSW
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
VIC
3199 - Frankston - Peninsula Health Frankston Hospital
NZ
NZ.0627 - Epsom - Mercy Ascot Hospital's Harbour Cancer & Wellness Centre
NZ.6035 - Wellington - Bowen Hospital
NCT06757634
Advanced
Phase 3
Recruiting
VIKTORIA-2: A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy and Safety of Gedatolisib With Endocrine Therapy and Palbociclib vs Endocrine Therapy and Ribociclib as
First-Line
Treatment in Patients With HR-Positive and HER2-Negative Advanced Breast Cancer (
CELC-G-302
)
CDK4/6 inhibitor
pan-PI3K/mTORC1/mTORC2 inhibitor
Breast cancer
NOT HER2-positive breast cancer
NOT Triple-negative breast cancer
NSW
2076 - Wahroonga - Sydney Adventist Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
QLD
4215 - Southport - ICON Cancer Care
4575 - Sunshine Coast - Sunshine Coast University Private Hospital
SA
5000 - South Australia - GenesisCare St Andrews Hospital
5011 - Woodville South - The Queen Elizabeth Hospital
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
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Recruitment Status
Recruiting (4)
Recruitment Country and State
NSW (4)
VIC (4)
SA (2)
QLD (2)
WA (2)
NZ (1)
Phase
Phase 2 / Phase 3 (1)
Phase 3 (3)
Trial Type
Advanced (4)
Cancer Therapy Class
PD-1/PD-L1
50%
PD-L1
25%
VEGFA
25%
EGFR
25%
ERBB3
25%
PD-1
25%
Trop2
25%
CDK4
25%
CDK6
25%
ER
25%
PI3K
25%
PI3Kalpha
25%
mTOR
25%
mTORC1
25%
mTORC2
25%
oestrogen axis
25%
Facility
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
3199 - Frankston - Peninsula Health Frankston Hospital (2)
5000 - South Australia - GenesisCare St Andrews Hospital (2)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (2)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
3168 - Clayton - Monash Children's Hospital (1)
2109 - North Ryde - Macquarie University Hospital (1)
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital (1)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
NZ.0627 - Epsom - Mercy Ascot Hospital's Harbour Cancer & Wellness Centre (1)
NZ.6035 - Wellington - Bowen Hospital (1)
2076 - Wahroonga - Sydney Adventist Hospital (1)
4215 - Southport - ICON Cancer Care (1)
4575 - Sunshine Coast - Sunshine Coast University Private Hospital (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
Cancer Type
Breast cancer
Cancer
Solid tumour
Breast adenocarcinoma
Triple-negative breast cancer
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