ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/endometrial/metastatic/mmr-deficient
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Gynaecological / Endometrial - Metastatic / MMR deficient
4
trial(s) found.
NCT06989112
Advanced
Phase 3
Recruiting
DESTINY-Endometrial01: An Open-Label, Sponsor-Blinded, Randomized, Controlled, Multicenter, Phase III Study of Trastuzumab Deruxtecan (T-DXd) Plus Rilvegostomig or Pembrolizumab vs Chemotherapy Plus Pembrolizumab as First-Line Therapy of HER2-Expressing (IHC 3+/2+),
Mismatch
Repair Proficient (pMMR), Primary Advanced or Recurrent Endometrial Cancer (
DE-01
)
anti-ERBB2 antibody-drug conjugate
anti-PD-1 monoclonal antibody
bispecific PD-1/TIGIT antibody
Endometrial cancer
NSW
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
VIC
3002 - East Melbourne - Epworth Freemasons
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
NCT06974110
Advanced
Phase 1
Recruiting
A Phase 1 Study of MOMA-341 as Monotherapy or Combination Therapy in Participants With Advanced or Metastatic Solid Tumors (
MOMA-341-001
)
WRN inhibitor
Cancer
Colorectal cancer
Endometrial cancer
Gastric cancer
Solid tumour
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3168 - Clayton - Monash Medical Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6009 - Nedlands - Linear Clinical Research
NCT06710847
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 First-Time-in-Human, Open-label, Multicenter, Dose Escalation and Expansion Study of the Oral DNA Helicase Werner Inhibitor (WRNi) GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Adult Participants With
Mismatch
Repair-
deficient
(
dMMR
) or Microsatellite Instability-High (
MSI
-H) Solid Tumors (
SYLVER
)
WRN inhibitor
Cancer
Colon adenocarcinoma
Endometrial cancer
Rectal adenocarcinoma
Solid tumour
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT05086692
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors (
ABILITY-1
)
IL-2 superkine
Acral lentiginous melanoma
Bladder cancer
Cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial cancer
Endometrial carcinoma
Epithelial Ovarian Cancer
Fallopian tube cancer
Gastric cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Merkel cell carcinoma
Mucosal melanoma
Non-melanoma skin cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pleural mesothelioma
Primary peritoneal serous carcinoma
Skin cancer
Solid tumour
Squamous non-small-cell lung cancer
Triple-negative breast cancer
dMMR solid cancer
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
QLD
4120 - Greenslopes - Greenslopes Private Hospital
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic
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Recruitment Status
Recruiting (4)
Recruitment Country and State
NSW (3)
QLD (3)
VIC (3)
WA (2)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 3 (1)
Trial Type
Advanced (4)
Cancer Therapy Class
PD-1
50%
PD-1/PD-L1
50%
WRN
50%
ERBB2
25%
TIGIT
25%
IL-2
25%
Facility
2031 - Randwick - Scientia Clinical Research Ltd (2)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
3002 - East Melbourne - Epworth Freemasons (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
6009 - Nedlands - Linear Clinical Research (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
2109 - North Ryde - Macquarie University Hospital (1)
4120 - Greenslopes - Greenslopes Private Hospital (1)
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic (1)
Cancer Type
Cancer
Endometrial cancer
Gynaecological cancer
Solid tumour
Colorectal cancer
Gastrointestinal cancer
Lower gastrointestinal cancer
Gastric cancer
Gastroesophageal cancer
Upper gastrointestinal cancer
Colon adenocarcinoma
Colorectal adenocarcinoma
Rectal adenocarcinoma
Acral lentiginous melanoma
Biomarker-defined solid tumour
Bladder cancer
Breast adenocarcinoma
Breast cancer
Cervical cancer
Clear cell renal cell carcinoma
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial carcinoma
Epithelial Ovarian Cancer
Exocrine pancreatic cancer
Fallopian tube cancer
Gastric carcinoma
Gastroesophageal junction adenocarcinoma
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Head and neck squamous cell carcinoma
High-grade serous carcinoma of the ovary, fallopian tube, and peritoneum
Kidney cancer
Lung cancer
MSI-H/dMMR solid tumour
Melanoma
Merkel cell carcinoma
Mesothelioma
Mucosal melanoma
Non-melanoma skin cancer
Non-small cell lung cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pancreatic cancer
Pancreatobiliary cancer
Peritoneal cancer
Pleural mesothelioma
Primary peritoneal serous carcinoma
Respiratory tract cancer
Skin cancer
Squamous non-small-cell lung cancer
Thoracic cancer
Triple-negative breast cancer
Urogenital cancer
Viral-related cancer
dMMR solid cancer
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