ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/non-melanoma-skin/adjuvant-neoadjuvant
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
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Melanoma and skin / Non-melanoma skin - Adjuvant/neoadjuvant
6
trial(s) found.
NCT06568172
Curative
Phase 3
Recruiting
Randomized Phase III Trial of Neoadjuvant Immunotherapy With Response-Adapted Treatment Versus Standard-of-Care Treatment for Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma (C-PRE) (
NCI-2024-03425
)
Cemiplimab
Radiotherapy
anti-PD-1 monoclonal antibody
cancer therapy
cancer therapy,PD-1-targeting
cancer therapy,PD-1/PD-L1-targeting
immune checkpoint blockade
immune checkpoint blockade,PD-1-targeting
immuno-oncology therapy,PD-1-targeting
Cutaneous squamous cell carcinoma
Salivary gland lymphoepithelial carcinoma
Sarcoma
Squamous cell carcinoma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2500 - Wollongong - Wollongong Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3065 - Fitzroy - St Vincent's Hospital Melbourne
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4812 - Townsville - Townsville University Hospital
NCT06418724
Curative
Phase 2
Not yet recruiting
Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma (
NEOPECS
)
Cemiplimab
Cetuximab
anti-EGFR monoclonal antibody
anti-PD-1 monoclonal antibody
cancer therapy
cancer therapy,EGFR-targeting
cancer therapy,PD-1-targeting
cancer therapy,PD-1/PD-L1-targeting
immune checkpoint blockade
immune checkpoint blockade,PD-1-targeting
immuno-oncology therapy,EGFR-targeting
immuno-oncology therapy,PD-1-targeting
Cutaneous squamous cell carcinoma
NCT06288191
Curative
Phase 2
Recruiting
A Phase 2, Open Label, Single Arm, Clinical Trial of Neoadjuvant Nivolumab and Relatlimab in Stage II To IV (M0) Resectable Cutaneous Squamous Cell Carcinoma (
MIA2023-490
)
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
NCT06151236
Curative
Phase 2
Recruiting
A Phase 2, Open Label, Single Arm Clinical Trial of Neoadjuvant Nivolumab and Relatlimab in Stage I To III Resectable Merkel Cell Carcinoma (
MIA2023-489
)
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Merkel cell carcinoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
NCT05025813
Curative
Phase 2
Recruiting
A Phase 2 Study of De-escalation in Resectable, Locally Advanced Cutaneous Squamous Cell Carcinoma With the Use of Neoadjuvant Pembrolizumab -
DESQUAMATE
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Head and neck cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12618001351202
Curative
Not Applicable
Not yet recruiting
A prospective case series evaluating neo-adjuvant use of Vismodegib in patients with periocular basal cell carcinoma to evaluate reduction in clinical and surgical tumour margins
SMO inhibitor,first generation
Cancer
Cutaneous basal cell carcinoma
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
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Recruitment Status
Recruiting (4)
Not yet recruiting (2)
Recruitment Country and State
NSW (4)
QLD (2)
VIC (1)
SA (1)
Phase
Phase 2 (4)
Phase 3 (1)
Trial Type
Curative (6)
Cancer Therapy Class
PD-1
83%
PD-1/PD-L1
83%
LAG3
33%
EGFR
17%
SMO
17%
Facility
2050 - Camperdown - Chris O'Brien Lifehouse (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre (2)
2500 - Wollongong - Wollongong Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
4812 - Townsville - Townsville University Hospital (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
Cancer Type
Cancer
Non-melanoma skin cancer
Skin cancer
Solid tumour
Cutaneous squamous cell carcinoma
Head and neck cancer
Carcinoma
Salivary gland cancer
Salivary gland lymphoepithelial carcinoma
Sarcoma
Squamous cell carcinoma
Merkel cell carcinoma
Cutaneous basal cell carcinoma
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