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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/non-melanoma-skin/advanced-metastatic
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Melanoma and skin / Non-melanoma skin - Advanced/metastatic
8
trial(s) found.
NCT05086692
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors (
ABILITY-1
)
IL-2 superkine
Acral lentiginous melanoma
Bladder cancer
Cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial carcinoma
Epithelial Ovarian Cancer
Fallopian tube cancer
Gastric cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Merkel cell carcinoma
Mucosal melanoma
Non-melanoma skin cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pleural mesothelioma
Primary peritoneal serous carcinoma
Skin cancer
Solid tumour
Squamous non-small-cell lung cancer
Triple-negative breast cancer
dMMR solid cancer
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
QLD
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation
NCT04429542
Advanced
Phase 1
Recruiting
First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFβ Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-Driven Advanced Solid Tumors (
BCA101X1101
)
bifunctional EGFR/TGF-beta fusion protein
Anal squamous cell carcinoma
Carcinoma
Colorectal cancer
Cutaneous squamous cell carcinoma
Epithelial Ovarian Cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Pancreatic cancer
Squamous cell carcinoma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
NCT03787602
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1b/2, Open-Label Study Evaluating the Safety and Efficacy of KRT-232 in Patients With p53 Wild-Type (p53WT) Merkel Cell Carcinoma (MCC) Who Have Failed Anti-PD-1 or Anti-PD-L1 Immunotherapy, or in Combination With Avelumab in MCC Patients Who Are Anti-PD-1 or Anti-PD-L1 Treatment Naïve (
KRT-232-103
)
MDM2 inhibitor
anti-PD-L1 monoclonal antibody
Merkel cell carcinoma
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12625000197437
Advanced
Phase 2
Not yet recruiting
A single arm, phase II trial of Cemiplimab in Head and Neck Cutaneous Squamous Cell Carcinoma with Large Nerve Perineural Spread (
NIL-Known
)
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12619001298101
Advanced
Phase 2
Not yet recruiting
A Phase IIa Study to assess the Efficacy and Safety of ASN-002 alone and in combination with chemotherapy in adult participants with Low-Risk Basal Cell Carcinomas (
ASN-002-IL
)
SYK/JAK inhibitor
Cutaneous basal cell carcinoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT06036836
Advanced
Phase 2
Active not recruiting
A Multicenter, Randomized, Double-Blind, Phase 2, Basket Study of MK-4280A, a Coformulation of Favezelimab (MK-4280) With Pembrolizumab (MK-3475) in Selected Solid Tumors (KeyForm-010) (
4280A-010
)
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Endometrial carcinoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
NCT05888844
Advanced
Phase 2
Active not recruiting
A Phase 2 Study Evaluating INCB099280 in Participants With Advanced Squamous Cell Carcinoma (
INCB-99280-212
)
PD-L1 inhibitor,oral
Cutaneous squamous cell carcinoma
NSW
2640 - Albury - Albury Wodonga Regional Cancer Centre
VIC
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital
NZ
NZ.3210 - Hamilton - Waikato Hospital
NCT05878288
Advanced
Phase 2
Active not recruiting
Comprehensive and Deep Profiling in Cutaneous Squamous Cell Carcinomas to Unravel Treatment Efficacy in Immunotherapy Treated Patients (
DISCERN
)
Cemiplimab
anti-PD-1 monoclonal antibody
cancer therapy
cancer therapy,PD-1-targeting
cancer therapy,PD-1/PD-L1-targeting
immune checkpoint blockade
immune checkpoint blockade,PD-1-targeting
immuno-oncology therapy,PD-1-targeting
Cancer
Cutaneous squamous cell carcinoma
Non-melanoma skin cancer
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
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Recruitment Status
Recruiting (3)
Active not recruiting (3)
Not yet recruiting (1)
Not yet recruiting (1)
Recruitment Country and State
QLD (6)
NSW (4)
VIC (4)
WA (1)
NZ (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 2 (5)
Trial Type
Advanced (8)
Cancer Therapy Class
PD-1/PD-L1
88%
PD-1
63%
PD-L1
25%
IL-2
13%
MDM2
13%
JAK
13%
SYK
13%
LAG3
13%
VEGF
13%
Facility
4102 - Woolloongabba - Princess Alexandra Hospital (3)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (2)
2031 - Randwick - Scientia Clinical Research Ltd (1)
2109 - North Ryde - Macquarie University Hospital (1)
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital (1)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
2640 - Albury - Albury Wodonga Regional Cancer Centre (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
3168 - Clayton - Monash Medical Centre (1)
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital (1)
NZ.3210 - Hamilton - Waikato Hospital (1)
Cancer Type
Cancer
Non-melanoma skin cancer
Skin cancer
Solid tumour
Cutaneous squamous cell carcinoma
Gynaecological cancer
Colorectal cancer
Cutaneous basal cell carcinoma
Endometrial cancer
Endometrial carcinoma
Epithelial Ovarian Cancer
Gastrointestinal cancer
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Lower gastrointestinal cancer
Merkel cell carcinoma
Ovarian cancer
Pancreatic cancer
Pancreatobiliary cancer
Upper gastrointestinal cancer
Viral-related cancer
Acral lentiginous melanoma
Biomarker-defined solid tumour
Bladder cancer
Breast adenocarcinoma
Breast cancer
Cervical cancer
Clear cell renal cell carcinoma
Cutaneous melanoma
Exocrine pancreatic cancer
Fallopian tube cancer
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
High-grade serous carcinoma of the ovary, fallopian tube, and peritoneum
Kidney cancer
Lung cancer
MSI-H/dMMR solid tumour
Melanoma
Mesothelioma
Mucosal melanoma
Non-small cell lung cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Pancreatic adenocarcinoma
Peritoneal cancer
Pleural mesothelioma
Primary peritoneal serous carcinoma
Respiratory tract cancer
Squamous non-small-cell lung cancer
Thoracic cancer
Triple-negative breast cancer
Urogenital cancer
dMMR solid cancer
Anal cancer
Anal squamous cell carcinoma
Carcinoma
Squamous cell carcinoma
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