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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/non-melanoma-skin/advanced-metastatic
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
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Melanoma and skin / Non-melanoma skin - Advanced/metastatic
5
trial(s) found.
NCT05086692
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors (
ABILITY-1
)
IL-2 superkine
Acral lentiginous melanoma
Bladder cancer
Cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial cancer
Endometrial carcinoma
Epithelial Ovarian Cancer
Fallopian tube cancer
Gastric cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Merkel cell carcinoma
Mucosal melanoma
Non-melanoma skin cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pleural mesothelioma
Primary peritoneal serous carcinoma
Skin cancer
Solid tumour
Squamous non-small-cell lung cancer
Triple-negative breast cancer
dMMR solid cancer
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
QLD
4120 - Greenslopes - Greenslopes Private Hospital
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic
NCT04429542
Advanced
Phase 1
Recruiting
First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFβ Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-Driven Advanced Solid Tumors (
BCA101X1101
)
bifunctional EGFR/TGF-beta fusion protein
Anal squamous cell carcinoma
Carcinoma
Colorectal cancer
Cutaneous squamous cell carcinoma
Epithelial Ovarian Cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Pancreatic cancer
Squamous cell carcinoma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
NCT03787602
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1b/2, Open-Label Study Evaluating the Safety and Efficacy of KRT-232 in Patients With p53 Wild-Type (p53WT) Merkel Cell Carcinoma (MCC) Who Have Failed Anti-PD-1 or Anti-PD-L1 Immunotherapy, or in Combination With Avelumab in MCC Patients Who Are Anti-PD-1 or Anti-PD-L1 Treatment Naïve (
KRT-232-103
)
MDM2 inhibitor
anti-PD-L1 monoclonal antibody
Merkel cell carcinoma
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12625000197437
Advanced
Phase 2
Not yet recruiting
A single arm, phase II trial of Cemiplimab in Head and Neck Cutaneous Squamous Cell Carcinoma with Large Nerve Perineural Spread (
NIL-Known
)
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12619001298101
Advanced
Phase 2
Not yet recruiting
A Phase IIa Study to assess the Efficacy and Safety of ASN-002 alone and in combination with chemotherapy in adult participants with Low-Risk Basal Cell Carcinomas (
ASN-002-IL
)
SYK/JAK inhibitor
Cutaneous basal cell carcinoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
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Recruitment Status
Recruiting (3)
Not yet recruiting (2)
Recruitment Country and State
QLD (4)
NSW (2)
VIC (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 2 (2)
Trial Type
Advanced (5)
Cancer Therapy Class
PD-1/PD-L1
80%
PD-1
60%
IL-2
20%
MDM2
20%
PD-L1
20%
JAK
20%
SYK
20%
Facility
4102 - Woolloongabba - Princess Alexandra Hospital (2)
2031 - Randwick - Scientia Clinical Research Ltd (1)
2109 - North Ryde - Macquarie University Hospital (1)
4120 - Greenslopes - Greenslopes Private Hospital (1)
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
Cancer Type
Cancer
Non-melanoma skin cancer
Skin cancer
Solid tumour
Cutaneous squamous cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Epithelial Ovarian Cancer
Gastrointestinal cancer
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Lower gastrointestinal cancer
Merkel cell carcinoma
Ovarian cancer
Pancreatic cancer
Pancreatobiliary cancer
Upper gastrointestinal cancer
Viral-related cancer
Acral lentiginous melanoma
Biomarker-defined solid tumour
Bladder cancer
Breast adenocarcinoma
Breast cancer
Cervical cancer
Clear cell renal cell carcinoma
Cutaneous melanoma
Endometrial cancer
Endometrial carcinoma
Exocrine pancreatic cancer
Fallopian tube cancer
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
High-grade serous carcinoma of the ovary, fallopian tube, and peritoneum
Kidney cancer
Lung cancer
MSI-H/dMMR solid tumour
Melanoma
Mesothelioma
Mucosal melanoma
Non-small cell lung cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Pancreatic adenocarcinoma
Peritoneal cancer
Pleural mesothelioma
Primary peritoneal serous carcinoma
Respiratory tract cancer
Squamous non-small-cell lung cancer
Thoracic cancer
Triple-negative breast cancer
Urogenital cancer
dMMR solid cancer
Anal cancer
Anal squamous cell carcinoma
Carcinoma
Squamous cell carcinoma
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