ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/non-small-cell-lung/advanced-metastatic/driverless/first-line-maintenance
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Respiratory / Non small cell lung - Advanced/metastatic / Driverless / First line, maintenance
11
trial(s) found.
NCT07361510
Advanced
Phase 3
Not yet recruiting
ROSETTA Lung-202: A Randomized, Double-Blind, Phase 3 Study of Pumitamig Monotherapy Compared to Pembrolizumab as
First-line
Treatment in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With PD-L1 ≥ 50%. (
CA266-0002
)
anti-PD-1 monoclonal antibody
bispecific PD-L1/VEGFA antibody
Non-small cell lung cancer
NSW
2259 - Wyong - Wyong Hospital
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre
VIC
3066 - Epping - Northern Hospital
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
SA
5112 - Elizabeth Vale - Lyell McEwin Hospital
WA
6027 - Joondalup - Joondalup Health Campus
NCT07221474
Advanced
Phase 2
Recruiting
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of V940 in Combination With Pembrolizumab and Chemotherapy as
First-Line
Treatment for Participants With Metastatic Squamous NSCLC (INTerpath-013) (
INTerpath-13
)
anti-PD-1 monoclonal antibody
mRNA personalised cancer vaccine
placebo
Squamous non-small-cell lung cancer
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
WA
6009 - Nedlands - One Clinical Research
NCT07063745
Advanced
Phase 2 / Phase 3
Recruiting
A Randomized Phase 2/3 Study of BMS-986504 in Combination With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in
First-line
Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion (
MountainTAP-29
)
PRMT5 inhibitor,MTA-co-operative
anti-PD-1 monoclonal antibody
placebo
Non-small cell lung cancer
NSW
2170 - Liverpool - Liverpool Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4575 - Birtinya - Sunshine Coast University Hospital
SA
5112 - Elizabeth Vale - Lyell McEwin Hospital
TAS
7000 - Hobart - Royal Hobart Hospital
NCT06868277
Advanced
Phase 3
Recruiting
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab Monotherapy for the
First-line
Treatment of Patients With PD-L1-high Metastatic Non-small Cell Lung Cancer (ARTEMIDE-Lung04) (
ARTEMIDELung04
)
anti-PD-1 monoclonal antibody
bispecific PD-1/TIGIT antibody
Non-small cell lung cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
TAS
7000 - Hobart - Royal Hobart Hospital
NCT06765109
Advanced
Phase 3
Recruiting
A Phase 3 Study of the Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor NVL-655 Compared to Alectinib in
First-Line
Treatment of Patients With ALK-Positive Advanced Non-Small Cell Lung Cancer (
ALKAZAR
)
ALK/RET inhibitor
ALK inhibitor,fourth generation
ALK inhibitor,second generation
Lymphoma
Non-small cell lung cancer
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
NCT06712316
Advanced
Phase 2 / Phase 3
Recruiting
A Phase II/III, Multisite, Randomized Master Protocol for a Global Trial of BNT327 in Combination With Chemotherapy and Other Investigational Agents in
First-line
Non-small Cell Lung Cancer (
BNT327-06
)
bispecific PD-L1/VEGFA antibody
Non-small cell lung cancer
NSW
2500 - Wollongong - Cancer Care Wollongong
2800 - Orange - Orange Hospital-Cancer Centre Clinical Trials Unit
2830 - Dubbo - Dubbo Base Hospital
VIC
3021 - St Albans - Western Health - Sunshine Hospital
3168 - Clayton - Monash Medical Centre
3199 - Frankston - Peninsula Health Frankston Hospital
QLD
4812 - Hyde Park - Icon Cancer Centre Townsville
4870 - Cairns - Cairns Base Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5037 - Kurralta Park - Icon Cancer Centre Adelaide
5042 - Bedford Park - Flinders Medical Centre
NCT06692738
Advanced
Phase 3
Recruiting
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the
First-line
Treatment of Patients With Metastatic Squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung02) (
D702BC00001
)
anti-PD-1 monoclonal antibody
bispecific PD-1/TIGIT antibody
Non-small cell lung cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2500 - Wollongong - Wollongong Hospital
QLD
4215 - Southport - Gold Coast University Hospital
4812 - Hyde Park - Icon Cancer Centre Townsville
NCT06627647
Advanced
Phase 3
Recruiting
A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the
First-line
Treatment of Patients With Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03) (
D702FC00001
)
anti-PD-1 monoclonal antibody
bispecific PD-1/TIGIT antibody
Non-squamous non-small-cell lung cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2500 - Wollongong - Wollongong Hospital
QLD
4215 - Southport - Gold Coast University Hospital
4812 - Hyde Park - Icon Cancer Centre Townsville
NCT06236438
Advanced
Phase 2 / Phase 3
Recruiting
A Randomized, Phase 2/3 Study to Evaluate the Optimal Dose, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus Pembrolizumab Plus Chemotherapy in
Untreated
Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (
LIVIGNO-4
)
anti-GARP monoclonal antibody
anti-PD-1 monoclonal antibody
Non-small cell lung cancer
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre
ACT
2605 - Garran - The Canberra Hospital
NCT06170788
Advanced
Phase 3
Recruiting
A Randomized, Open-label, Phase 3 Study of MK-2870 in Combination With Pembrolizumab Compared to Pembrolizumab Monotherapy in the
First-line
Treatment of Participants With Metastatic Non-small Cell Lung Cancer With PD-L1 TPS Greater Than or Equal to 50% (
TroFuse-007
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Non-small cell lung cancer
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2444 - Port Macquarie - Mid North Coast Cancer Institute-Port Macquarie Base Hospital
VIC
3066 - Epping - Northern Hospital
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
NCT05215340
Advanced
Phase 3
Recruiting
A Randomized, Open-label, Phase 3 Trial of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in Treatment-
naïve
Subjects With Advanced or Metastatic PD-L1 High (TPS ≥50%) Non-small Cell Lung Cancer Without Actionable Genomic Alterations (
TROPION-Lung08
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Non-small cell lung cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3199 - Frankston - Peninsula Health Frankston Hospital
SA
5011 - Woodville South - The Queen Elizabeth Hospital
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Recruitment Status
Recruiting (10)
Not yet recruiting (1)
Recruitment Country and State
NSW (10)
VIC (6)
QLD (5)
SA (4)
WA (2)
ACT (2)
TAS (2)
Phase
Phase 2 (1)
Phase 2 / Phase 3 (3)
Phase 3 (7)
Trial Type
Advanced (11)
Cancer Therapy Class
PD-1
91%
PD-1/PD-L1
91%
TIGIT
27%
PD-L1
18%
VEGFA
18%
Trop2
18%
PRMT5
9%
ALK
9%
RET
9%
GARP
9%
Facility
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (4)
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital (3)
4812 - Hyde Park - Icon Cancer Centre Townsville (3)
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre (2)
3066 - Epping - Northern Hospital (2)
5112 - Elizabeth Vale - Lyell McEwin Hospital (2)
2605 - Garran - The Canberra Hospital (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
7000 - Hobart - Royal Hobart Hospital (2)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (2)
3199 - Frankston - Peninsula Health Frankston Hospital (2)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (2)
2500 - Wollongong - Wollongong Hospital (2)
4215 - Southport - Gold Coast University Hospital (2)
2259 - Wyong - Wyong Hospital (1)
6027 - Joondalup - Joondalup Health Campus (1)
6009 - Nedlands - One Clinical Research (1)
2170 - Liverpool - Liverpool Hospital (1)
4575 - Birtinya - Sunshine Coast University Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
2500 - Wollongong - Cancer Care Wollongong (1)
2800 - Orange - Orange Hospital-Cancer Centre Clinical Trials Unit (1)
2830 - Dubbo - Dubbo Base Hospital (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4870 - Cairns - Cairns Base Hospital (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
5037 - Kurralta Park - Icon Cancer Centre Adelaide (1)
5042 - Bedford Park - Flinders Medical Centre (1)
2444 - Port Macquarie - Mid North Coast Cancer Institute-Port Macquarie Base Hospital (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
Cancer Type
Cancer
Lung cancer
Non-small cell lung cancer
Respiratory tract cancer
Solid tumour
Thoracic cancer
Squamous non-small-cell lung cancer
Haematological malignancy
Lymphoma
Non-squamous non-small-cell lung cancer
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