ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/oropharynx-and-larynx/recurrent-metastatic/first-line
Home
By cancer type
By drug class
By site
Data
FAQ
About
⚠
ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Head & neck and Neurological / Oropharynx and Larynx - Recurrent or metastatic / First line
5
trial(s) found.
NCT06806852
Advanced
Phase 1
Recruiting
A Phase Ib Open Label Randomised Clinical Trial to Evaluate Safety and Efficacy of BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Compared With Pembrolizumab Monotherapy for the
First-line
Treatment of Patients With Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (
1501-0002
)
anti-EGFR monoclonal antibody
anti-PD-1 monoclonal antibody
anti-SIRPa monoclonal antibody
Head and neck squamous cell carcinoma
NSW
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital
VIC
3220 - Geelong - Andrew Love Cancer Centre, University Hospital Geelong
NCT06788990
Advanced
Phase 2 / Phase 3
Recruiting
A Multicenter, Randomized, Double-blind, Phase 2/3 Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab for
First-Line
Treatment of PD-L1-positive, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (
FORTIFI-HN01
)
anti-PD-1 monoclonal antibody
bifunctional EGFR/TGF-beta fusion protein
placebo
Head and neck squamous cell carcinoma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre
VIC
3051 - North Melbourne - Melbourne Theranostic Innovation Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
QLD
4215 - Southport - ICON Cancer Care
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital
WA
6150 - Murdoch - Fiona Stanley Hospital
NZ
NZ.3010 - Rotorua - Rotorua Hospital
NCT06525220
Advanced
Phase 3
Recruiting
A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of Petosemtamab Plus Pembrolizumab vs Pembrolizumab in
First-line
Treatment of Recurrent or Metastatic PD-L1+ Head and Neck Squamous Cell Carcinoma (
MCLA-158-CL03
)
anti-PD-1 monoclonal antibody
bispecific EGFR/LGR5 antibody
Head and neck squamous cell carcinoma
NSW
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
NCT06295731
Advanced
Phase 2 / Phase 3
Recruiting
A Phase 2/3, Randomized Study of INBRX-106 Combined With Pembrolizumab Versus Pembrolizumab as
First Line
Treatment for Patients With Recurrent or Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC) Expressing PD-L1 (CPS ≥20) (
HexAgon-HN
)
anti-PD-1 monoclonal antibody
Head and neck squamous cell carcinoma
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT04534205
Advanced
Phase 2 / Phase 3
Recruiting
An Open-label Phase II/III Randomized Trial of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Monotherapy as a
First Line
Therapy in Patients With Unresectable Recurrent, or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Which is Positive for Human Papilloma Virus 16 (HPV16+) and Expresses PD-L1 (
AHEAD-MERIT
)
anti-PD-1 monoclonal antibody
vaccine therapy,HPV-E6/HPV-E7-targeting
Head and neck cancer
Head and neck squamous cell carcinoma
NSW
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
2500 - Wollongong - Wollongong Hospital
2200 - Bankstown - Bankstown-Lidcombe Hospital (WITHDRAWN)
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute (WITHDRAWN)
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
QLD
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5042 - Bedford Park - Flinders Medical Centre
Additional search terms:
API and Webpage URLs:
Copy /Bookmark
Filters
Recruitment Status
Recruiting (5)
Recruitment Country and State
NSW (4)
VIC (4)
QLD (2)
SA (2)
NZ (1)
WA (1)
Phase
Phase 1 (1)
Phase 2 / Phase 3 (3)
Phase 3 (1)
Trial Type
Advanced (5)
Cancer Therapy Class
PD-1
100%
PD-1/PD-L1
100%
EGFR
40%
SIRPa
20%
LGR5
20%
HPV-E6
20%
HPV-E7
20%
Facility
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital (2)
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital (2)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (2)
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital (1)
3220 - Geelong - Andrew Love Cancer Centre, University Hospital Geelong (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre (1)
3051 - North Melbourne - Melbourne Theranostic Innovation Centre (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
4215 - Southport - ICON Cancer Care (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
NZ.3010 - Rotorua - Rotorua Hospital (1)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
2200 - Bankstown - Bankstown-Lidcombe Hospital (1)
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute (1)
2500 - Wollongong - Wollongong Hospital (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
5042 - Bedford Park - Flinders Medical Centre (1)
Cancer Type
Cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Solid tumour
URLs for this search
API URL:
Copy
Bookmarkable URL:
Copy