ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/skin
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Melanoma and skin / Skin
22
trial(s) found.
NCT06999980
Curative
Phase 2
Not yet recruiting
A Phase II, Multicentre, Open Label, Randomised Clinical Trial of Nivolumab and Ipilimumab Combined With Relatlimab for Patients With Resectable Advanced Melanoma Identified as Poor Responders to Immunotherapy (
Neo-IRENIE
)
anti-CTLA4 monoclonal antibody
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Cutaneous melanoma
Mucosal melanoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
NCT06926075
Advanced
Phase 1
Not yet recruiting
An Adaptive Phase I/II Study of Kesonotide, a Novel hGIIA-vimentin Inhibitor, in Participants With Solid Tumours (
ADVICE
)
hGIIA-vimentin inhibitor
Breast cancer
Glioblastoma
Lung cancer
Ovarian cancer
Pancreatic cancer
Prostate cancer
Skin cancer
NCT06418724
Curative
Phase 2
Not yet recruiting
Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma (
NEOPECS
)
Cemiplimab
Cetuximab
anti-EGFR monoclonal antibody
anti-PD-1 monoclonal antibody
cancer therapy
cancer therapy,EGFR-targeting
cancer therapy,PD-1-targeting
cancer therapy,PD-1/PD-L1-targeting
immune checkpoint blockade
immune checkpoint blockade,PD-1-targeting
immuno-oncology therapy,EGFR-targeting
immuno-oncology therapy,PD-1-targeting
Cutaneous squamous cell carcinoma
NCT06305962
Radonc
Phase 1
Recruiting
Phase 0/1 Study of the Safety and Tolerability of 177Lu-RAD204, a Lutetium-177 Radiolabelled Single Domain Antibody Against Programmed Cell Death-Ligand 1 in Patients With Metastatic Solid Tumours (
177Lu-RAD204.2023.0001
)
radioconjugate,PD-L1-targeting
Cutaneous melanoma
Endometrial cancer
Head and neck squamous cell carcinoma
Non-small cell lung cancer
Small-cell lung cancer
Triple-negative breast cancer
NSW
2500 - Wollongong - Wollongong Hospital
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre
QLD
4215 - Southport - Gold Coast University Hospital
4509 - North Lakes - Icon Cancer Centre North Lakes
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6150 - Murdoch - GenesisCare Murdoch
NCT06288191
Curative
Phase 2
Recruiting
A Phase 2, Open Label, Single Arm, Clinical Trial of Neoadjuvant Nivolumab and Relatlimab in Stage II to IV (M0) Resectable Cutaneous Squamous Cell Carcinoma (
MIA2023-490
)
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
NCT06151236
Curative
Phase 2
Recruiting
A Phase 2, Open Label, Single Arm Clinical Trial of Neoadjuvant Nivolumab and Relatlimab in Stage I To III Resectable Merkel Cell Carcinoma (
MIA2023-489
)
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
Merkel cell carcinoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
NCT06022029
Haem
Phase 1
Recruiting
A Phase 1 Dose-Escalation and Expansion Study of Intratumorally Administered ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas (
ON-5001
)
STING agonist
anti-PD-1 monoclonal antibody
Bladder cancer
Cancer
Carcinoma
Cervical cancer
Diffuse large B-cell lymphoma
Follicular lymphoma
Head and neck squamous cell carcinoma
Lymphoma
Mantle cell lymphoma
Skin cancer
Triple-negative breast cancer
Uveal melanoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2500 - Wollongong - Wollongong Hospital
QLD
4215 - Southport - Tasman Oncology
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic
SA
5042 - Bedford Park - Southern Oncology Clinical Research Unit
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
NCT05267626
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2, First-in-Human, Open Label, Dose Escalation and Expansion Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer (
CP-AU-007-01
)
anti-IL-2 monoclonal antibody
Cancer
Cutaneous melanoma
Non-small cell lung cancer
Solid tumour
NSW
2228 - Miranda - Southside Cancer Care Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
3021 - St Albans - Western Health - Sunshine Hospital
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
3199 - Frankston - Peninsula Health Frankston Hospital
SA
5042 - Bedford Park - Southern Oncology Clinical Research Unit
NCT05086692
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors (
ABILITY-1
)
IL-2 superkine
Acral lentiginous melanoma
Bladder cancer
Cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial cancer
Endometrial carcinoma
Epithelial Ovarian Cancer
Fallopian tube cancer
Gastric cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Merkel cell carcinoma
Mucosal melanoma
Non-melanoma skin cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pleural mesothelioma
Primary peritoneal serous carcinoma
Skin cancer
Solid tumour
Squamous non-small-cell lung cancer
Triple-negative breast cancer
dMMR solid cancer
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
QLD
4120 - Greenslopes - Greenslopes Private Hospital
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic
NCT05025813
Curative
Phase 2
Recruiting
A Phase 2 Study of De-escalation in Resectable, Locally Advanced Cutaneous Squamous Cell Carcinoma With the Use of Neoadjuvant Pembrolizumab -
DESQUAMATE
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Head and neck cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
NCT04429542
Advanced
Phase 1
Recruiting
First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFβ Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-Driven Advanced Solid Tumors (
BCA101X1101
)
bifunctional EGFR/TGF-beta fusion protein
Anal squamous cell carcinoma
Carcinoma
Colorectal cancer
Cutaneous squamous cell carcinoma
Epithelial Ovarian Cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Pancreatic cancer
Squamous cell carcinoma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
NCT03947385
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of IDE196 in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions (
IDE196-001
)
PKC inhibitor
Colorectal cancer
Cutaneous melanoma
Solid tumour
Uveal melanoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
NCT03787602
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1b/2, Open-Label Study Evaluating the Safety and Efficacy of KRT-232 in Patients With p53 Wild-Type (p53WT) Merkel Cell Carcinoma (MCC) Who Have Failed Anti-PD-1 or Anti-PD-L1 Immunotherapy, or in Combination With Avelumab in MCC Patients Who Are Anti-PD-1 or Anti-PD-L1 Treatment Naïve (
KRT-232-103
)
MDM2 inhibitor
anti-PD-L1 monoclonal antibody
Merkel cell carcinoma
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
NCT03534947
Curative
Phase 2
Recruiting
A Pilot Study to Evaluate Short Term Neoadjuvant Sonidegib Followed by Surgery or Imiquimod in the Management of Basal Cell Carcinomas in Cosmetically Challenging Locations (
SONIB
)
SMO inhibitor,first generation
topical immune response modifier
Carcinoma
Cutaneous basal cell carcinoma
Skin cancer
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
ACTRN12625000197437
Advanced
Phase 2
Not yet recruiting
A single arm, phase II trial of Cemiplimab in Head and Neck Cutaneous Squamous Cell Carcinoma with Large Nerve Perineural Spread (
NIL-Known
)
anti-PD-1 monoclonal antibody
Cutaneous squamous cell carcinoma
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12624001342505
Advanced
Not Applicable
Not yet recruiting
A Prospective, Open-Label, Randomized, Controlled Post-Market Clinical Trial Investigating the Safety and Effectiveness of Human Amnion Membrane (AM) in a Cohort of Patients with Loss of Full Thickness Skin Graft Following Reconstruction of a Cutaneous Nasal Defect Secondary to Skin Cancer Resection.
Cytarabine
antimetabolite
cancer therapy
cytotoxic chemotherapy
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12624001101572
Curative
Not Applicable
Not yet recruiting
The safety and feasibility of exercise in patients with melanoma undergoing adjuvant immunotherapy with immune checkpoint inhibitor therapy – the
EXHIBIT
Study
Cutaneous melanoma
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
ACTRN12624000917538
Advanced
Phase 2
Not yet recruiting
Efficacy and safety of cetuximab and prochlorperazine combined for solid organ transplant patients with advanced Cutaneous Squamous Cell Carcinoma:
CetPro
study
anti-EGFR monoclonal antibody
antihistamine
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12624000911594
Advanced
Phase 3
Not yet recruiting
CICAFU
Trial: Randomised, controlled trial of CICAPLAST Baume B5+ versus standard of care on tolerability and observance of topical 5% 5-fluorouracil in Patients diagnosed with Actinic Keratoses (AK)
fluoropyrimidine
Skin cancer
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
ACTRN12619001298101
Advanced
Phase 2
Not yet recruiting
A Phase IIa Study to assess the Efficacy and Safety of ASN-002 alone and in combination with chemotherapy in adult participants with Low-Risk Basal Cell Carcinomas (
ASN-002-IL
)
SYK/JAK inhibitor
Cutaneous basal cell carcinoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
ACTRN12618001351202
Curative
Not Applicable
Not yet recruiting
A prospective case series evaluating neo-adjuvant use of Vismodegib in patients with periocular basal cell carcinoma to evaluate reduction in clinical and surgical tumour margins
SMO inhibitor,first generation
Cancer
Cutaneous basal cell carcinoma
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
ACTRN12615000190505
Radonc
Not Applicable
Not yet recruiting
A pilot study: Risk adapted hypofractionated radiotherapy in Merkel Cell Carcinoma of the elderly and/or the fragile patient assessing safety/efficacy. (
MP4-pilot-study.
)
radiotherapy
Merkel cell carcinoma
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Recruitment Status
Not yet recruiting (11)
Recruiting (11)
Recruitment Country and State
NSW (11)
QLD (10)
SA (4)
VIC (3)
WA (2)
Phase
Phase 1 (4)
Phase 1 / Phase 2 (4)
Phase 2 (9)
Phase 3 (1)
Trial Type
Advanced (11)
Curative (8)
Radonc (2)
Haem (1)
Cancer Therapy Class
PD-1/PD-L1
55%
PD-1
45%
LAG3
14%
PD-L1
14%
EGFR
9%
IL-2
9%
SMO
9%
CTLA4
5%
hGIIA-vimentin
5%
STING
5%
ALK
5%
MEK
5%
MET
5%
PKC
5%
ROS1
5%
MDM2
5%
JAK
5%
SYK
5%
Facility
4102 - Woolloongabba - Princess Alexandra Hospital (6)
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre (4)
2500 - Wollongong - Wollongong Hospital (2)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (2)
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic (2)
5042 - Bedford Park - Southern Oncology Clinical Research Unit (2)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (2)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre (1)
4215 - Southport - Gold Coast University Hospital (1)
4509 - North Lakes - Icon Cancer Centre North Lakes (1)
6150 - Murdoch - GenesisCare Murdoch (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
4215 - Southport - Tasman Oncology (1)
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital (1)
2228 - Miranda - Southside Cancer Care Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
2031 - Randwick - Scientia Clinical Research Ltd (1)
2109 - North Ryde - Macquarie University Hospital (1)
4120 - Greenslopes - Greenslopes Private Hospital (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre (1)
Cancer Type
Cancer
Skin cancer
Solid tumour
Non-melanoma skin cancer
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Cutaneous melanoma
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dMMR solid cancer
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Anal squamous cell carcinoma
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