ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/thyroid/differentiated
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Sarcoma, Endocrine, and Rare Cancers / Thyroid / Differentiated
7
trial(s) found.
NCT05503797
Advanced
Phase 2
Recruiting
A Phase 2 Master Protocol to Assess the Efficacy and Safety of FORE8394, an Inhibitor of BRAF Class 1 and Class 2 Alterations, in Participants With Cancer Harboring BRAF Alterations (
F8394-201
)
RAF dimer inhibitor
Cancer
Central nervous system cancer
Melanoma
NOT Colorectal adenocarcinoma
NOT Melanoma
NOT Non-small cell lung cancer
NOT Pancreatic adenocarcinoma
NOT Thyroid cancer
Solid tumour
Thyroid cancer
NSW
2031 - Randwick - Sydney Children's Hospital
2305 - New Lambton Heights - Newcastle Private Hospital
VIC
3004 - Melbourne, Southbank - Alfred Health
NCT05182931
Advanced
Phase 2
Recruiting
A Prospective, Multi-Centre Trial of TKI Redifferentiation Therapy in Patients With RAIR Thyroid Cancer (
I-FIRST
Study)
BRAF V600 inhibitor
BRAF inhibitor
Dabrafenib
MEK inhibitor
RAF inhibitor
Trametinib
cancer therapy
cancer therapy,BRAF-targeting
cancer therapy,BRAF V600-targeting
cancer therapy,MEK-targeting
cancer therapy,RAF-targeting
NOT Anaplastic thyroid cancer
Thyroid cancer
NSW
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
3181 - Prahran - The Alfred Hospital
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
NCT05024929
Paed
Recruiting
Targeted Therapy to Increase RAI Uptake in Patients With Metastatic DifferentiatedThyroid Cancer (
21-018612
)
Differentiated thyroid carcinoma
Papillary thyroid cancer
NSW
2145 - Westmead - The Children's Hospital at Westmead
NCT03175224
Advanced
Phase 2
Recruiting
Phase 1 / 2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects With Non-Small Cell Lung Cancer With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (
SPARTA
)
MET inhibitor,type 1
Cancer
Central nervous system cancer
Colon adenocarcinoma
Gastric cancer
Gastroesophageal junction adenocarcinoma
Glioblastoma
Kidney cancer
Lung cancer
MET:alteration
MET:fusion
Non-small cell lung cancer
Pancreatic cancer
Solid tumour
Thyroid cancer
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
NCT02628067
Advanced
Phase 2
Recruiting
A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects With Advanced Solid Tumors (KEYNOTE 158) (
KEYNOTE-158
)
anti-PD-1 monoclonal antibody
Anal cancer
Biliary tract cancer
Cancer
Cervical cancer
Cholangiocarcinoma
Colorectal cancer
Endometrial cancer
Endometrial carcinoma
Lung carcinoid tumour
Mesothelioma
Neuroendocrine tumour
Pancreatic neuroendocrine tumour
Salivary gland cancer
Salivary gland carcinoma
Small-cell lung cancer
Solid tumour
Thyroid cancer
Vulval cancer
NCT03906331
Advanced
Approved for marketing
Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation
RET-selective inhibitor
RET inhibitor
Selpercatinib
cancer therapy
cancer therapy,RET-targeting
Breast cancer
Colon adenocarcinoma
Medullary thyroid cancer
Non-small cell lung cancer
Pancreatic cancer
Papillary thyroid cancer
Solid tumour
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4032 - Chermside - The Prince Charles Hospital
WA
6009 - Nedlands - Linear Clinical Research
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NCT03170960
Advanced
Phase 1 / Phase 2
Unknown
A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors (
XL184-021
)
AXL/MET/RET/VEGFR/ROS1/KIT inhibitor
AXL inhibitor
KIT inhibitor
MET inhibitor,type 2
RET inhibitor
ROS1 inhibitor
VEGFR2 inhibitor
anti-PD-L1 monoclonal antibody
Differentiated thyroid carcinoma
NSW
2031 - Randwick - Prince of Wales Hospital
2050 - Camperdown - Chris O'Brien Lifehouse
2109 - North Ryde - Macquarie University Hospital
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital
2640 - Albury - Border Medical Oncology Research Unit
VIC
3021 - St Albans - Western Health - Sunshine Hospital
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Recruitment Status
Recruiting (5)
Approved for marketing (1)
Unknown (1)
Recruitment Country and State
NSW (5)
VIC (5)
QLD (2)
WA (2)
SA (1)
NZ (1)
Phase
Phase 1 / Phase 2 (1)
Phase 2 (4)
Trial Type
Advanced (6)
Paed (1)
Cancer Therapy Class
BRAF
29%
RAF
29%
MET
29%
PD-1/PD-L1
29%
RET
29%
BRAF V600
14%
MEK
14%
PD-1
14%
AR
14%
AXL
14%
CYP17A1
14%
KIT
14%
PD-L1
14%
ROS1
14%
VEGFR
14%
VEGFR2
14%
androgen axis
14%
Facility
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
2050 - Camperdown - Chris O'Brien Lifehouse (2)
2031 - Randwick - Sydney Children's Hospital (1)
2305 - New Lambton Heights - Newcastle Private Hospital (1)
3004 - Melbourne, Southbank - Alfred Health (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
3168 - Clayton - Monash Medical Centre (1)
3181 - Prahran - The Alfred Hospital (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
2145 - Westmead - The Children's Hospital at Westmead (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
4032 - Chermside - The Prince Charles Hospital (1)
6009 - Nedlands - Linear Clinical Research (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
2031 - Randwick - Prince of Wales Hospital (1)
2109 - North Ryde - Macquarie University Hospital (1)
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital (1)
2640 - Albury - Border Medical Oncology Research Unit (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
Cancer Type
Cancer
Endocrine gland cancer
Solid tumour
Thyroid cancer
Differentiated thyroid carcinoma
Colorectal cancer
Gastrointestinal cancer
Lower gastrointestinal cancer
Lung cancer
Pancreatic cancer
Pancreatobiliary cancer
Respiratory tract cancer
Thoracic cancer
Upper gastrointestinal cancer
Central nervous system cancer
Neurological cancer
Papillary thyroid cancer
Colon adenocarcinoma
Colorectal adenocarcinoma
Non-small cell lung cancer
Melanoma
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
Glioblastoma
Glioma
High-grade glioma
Kidney cancer
MET:alteration
MET:fusion
Malignant glioma
Oesophageal cancer
Urogenital cancer
Anal cancer
Biliary tract cancer
Carcinoma
Cervical cancer
Cholangiocarcinoma
Endometrial cancer
Endometrial carcinoma
Gastro-entero-pancreatic neuroendocrine tumour
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Hepatobiliary cancer
Lung carcinoid tumour
Mesothelioma
Neuroendocrine carcinoma
Neuroendocrine tumour
Pancreatic neuroendocrine tumour
Salivary gland cancer
Salivary gland carcinoma
Small-cell lung cancer
Small-cell neuroendocrine carcinoma
Vaginal and vulvar cancer
Viral-related cancer
Vulval cancer
Breast cancer
Medullary thyroid cancer
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