ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/urothelial/advanced-metastatic/subsequent
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Prostate and Urogenital / Urothelial - Advanced/metastatic / Subsequent
11
trial(s) found.
NCT07623369
Advanced
Phase 1
Recruiting
An Open-Label, Multicenter, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Preliminary Antitumor Activity of HH160 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors (
HH160-101
)
trispecific PD-1/VEGFA/CTLA4 antibody
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Endometrial cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Hepatocellular carcinoma
Non-small cell lung cancer
Small-cell lung cancer
Solid tumour
Triple-negative breast cancer
Urothelial carcinoma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
QLD
4215 - Southport - Tasman Oncology
NCT07545122
Advanced
Phase 1
Recruiting
A Phase 1a/1b, First Time in Human Study of
CT-202
, A Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, and Urothelial Cancers
anti-NECTIN4 antibody-drug conjugate
Colorectal cancer
Triple-negative breast cancer
Urothelial carcinoma
NSW
2076 - Wahroonga - Sydney Adventist Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
QLD
4215 - Southport - Tasman Oncology
WA
6009 - Nedlands - Linear Clinical Research
NCT07421700
Advanced
Phase 1 / Phase 2
Recruiting
AN INTERVENTIONAL PHASE 1B/2, OPEN-LABEL STUDY TO INVESTIGATE THE SAFETY, ANTITUMOR ACTIVITY, AND PHARMACOKINETICS OF PF 08634404 MONOTHERAPY OR IN COMBINATION WITH ENFORTUMAB VEDOTIN IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER (
C6461006
)
anti-NECTIN4 antibody-drug conjugate
Urothelial carcinoma
NSW
2109 - North Ryde - Macquarie University Hospital
VIC
3168 - Clayton - Monash Medical Centre
QLD
4066 - Auchenflower - Icon Cancer Centre at Wesley Hospital
NCT07106762
Advanced
Phase 2 / Phase 3
Recruiting
IZABRIGHT-Bladder01: A Randomized, Open-label, Phase 2/3 Trial of Izalontamab Brengitecan Versus Platinum-based Chemotherapy for Metastatic Urothelial Cancer in Participants With Disease Progression on or After an Immunotherapy-based Treatment (
CA244-0012
)
bispecific EGFR/ERBB3 antibody
Urothelial carcinoma
NSW
2065 - St Leonards - GenesisCare North Shore Private Hospital
2109 - North Ryde - Macquarie University Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
NCT06760819
Advanced
Phase 2
Recruiting
A Phase 2 Open-label Basket Study to Evaluate the Efficacy and Safety of Orally Administered Reversible Tyrosine Kinase Inhibitor BAY 2927088 in Participants With Metastatic or Unresectable Solid Tumors With HER2-activating Mutations (
panSOHO
)
EGFR/ERBB2 inhibitor,mutant-selective,non-covalent
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Endometrial cancer
NOT Biliary tract cancer
NOT Colorectal cancer
NOT Non-small cell lung cancer
NOT Urothelial carcinoma
Urothelial carcinoma
NSW
2109 - North Ryde - Macquarie University Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
QLD
4215 - Southport - ICON Cancer Care
NCT06581432
Advanced
Phase 2
Recruiting
Beamion PANTUMOR-1: A Phase II, Multicentre, Multicohort, Open-label Trial to Evaluate the Efficacy and Safety of Oral Zongertinib (BI 1810631) for the Treatment of Selected HER2-mutated or Overexpressed/Amplified Solid Tumours (
1479-0009
)
ERBB2 inhibitor,second generation
Cervical cancer
Gastroesophageal junction adenocarcinoma
NOT Breast cancer
NOT Colorectal adenocarcinoma
NOT Gastroesophageal cancer
NOT Gastroesophageal junction adenocarcinoma
NOT Pancreatic adenocarcinoma
NOT Pancreatic cancer
NOT Squamous non-small-cell lung cancer
Non-small cell lung cancer
Solid tumour
Urothelial carcinoma
NSW
2065 - St Leonards - GenesisCare North Shore Private Hospital
2109 - North Ryde - Macquarie University Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
NCT06330064
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1B/2 Pan-Tumor, Open-Label Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) (
DS7300-203
)
anti-B7H3 antibody-drug conjugate,topoisomerase inhibitor 1-payload
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Cutaneous melanoma
Endometrial cancer
Gastrooesophageal adenicarcoma
Head and neck squamous cell carcinoma
Hepatocellular carcinoma
NOT Sarcoma
Ovarian cancer
Pancreatic adenocarcinoma
Urothelial carcinoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2065 - St Leonards - GenesisCare North Shore Private Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
NCT05562830
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Study of Investigational Agents With or Without Pembrolizumab in Participants With PD-1/L1 Refractory Locally Advanced or Metastatic Urothelial Carcinoma (KEYMAKER-U04): Substudy 04A (
3475-04A
)
anti-PD-1 monoclonal antibody
Urothelial carcinoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT04895709
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors (
CA052-002
)
anti-CCR8 monoclonal antibody
Cervical cancer
Clear cell renal cell carcinoma
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Microsatellite stable colorectal cancer
Non-small cell lung cancer
Ovarian cancer
Pancreatic adenocarcinoma
Triple-negative breast cancer
Urothelial carcinoma
NSW
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
2170 - Liverpool - Liverpool Hospital
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6009 - Nedlands - One Clinical Research
NCT04879329
Advanced
Phase 2
Recruiting
A Phase 2 Multi-Cohort, Open-Label, Multi-Center Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin (RC48-ADC) Alone or in Combination With Pembrolizumab in Subjects With Locally-Advanced Unresectable or Metastatic Urothelial Carcinoma That Expresses HER2 (
RC48G001
)
anti-ERBB2 antibody-drug conjugate,MMAE-payload
anti-PD-1 monoclonal antibody
Urothelial carcinoma
NSW
2065 - St Leonards - GenesisCare North Shore Private Hospital
2109 - North Ryde - Macquarie University Hospital
2999 - Unspecified - Clinical Trial Site NSW - GenesisCare
VIC
3199 - Frankston - Peninsula Health Frankston Hospital
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5112 - Elizabeth Vale - Lyell McEwin Hospital
NCT05642949
Advanced
Phase 1 / Phase 2
Unknown
Phase 1/2, Multi-center, Open-label, Dose Escalation and Cohort Expansion Study to Evaluate the Safety/Tolerability, Pharmacokinetics and Efficacy of MHB036C in Participants With Advanced or Metastatic Solid Tumors (
MHB036C-CP001EN
)
anti-Trop2 antibody-drug conjugate
Breast cancer
Endometrial cancer
Gastric cancer
Head and neck squamous cell carcinoma
Non-small cell lung cancer
Oesophageal squamous cell carcinoma
Ovarian cancer
Pancreatic adenocarcinoma
Prostate cancer
Small-cell lung cancer
Solid tumour
Sweat gland carcinoma
Urothelial carcinoma
VIC
3144 - Malvern - GenesisCare Cabrini, Cabrini Hospital
QLD
4217 - Benowa - Pindara Private Hospital
SA
5042 - Bedford Park - Southern Oncology Clinical Research Unit
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Recruitment Status
Recruiting (10)
Unknown (1)
Recruitment Country and State
QLD (10)
NSW (9)
VIC (5)
WA (4)
SA (3)
Phase
Phase 1 (2)
Phase 1 / Phase 2 (5)
Phase 2 (3)
Phase 2 / Phase 3 (1)
Trial Type
Advanced (11)
Cancer Therapy Class
PD-1
45%
PD-1/PD-L1
45%
ERBB2
27%
VEGFA
18%
Nectin4
18%
EGFR
18%
CTLA4
9%
VEGF
9%
ERBB3
9%
B7H3
9%
ROR1
9%
CCR8
9%
PD-L1
9%
Trop2
9%
Facility
2109 - North Ryde - Macquarie University Hospital (5)
2065 - St Leonards - GenesisCare North Shore Private Hospital (4)
4102 - Woolloongabba - Princess Alexandra Hospital (4)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (3)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (2)
4215 - Southport - Tasman Oncology (2)
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital (2)
2076 - Wahroonga - Sydney Adventist Hospital (1)
6009 - Nedlands - Linear Clinical Research (1)
3168 - Clayton - Monash Medical Centre (1)
4066 - Auchenflower - Icon Cancer Centre at Wesley Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
4215 - Southport - ICON Cancer Care (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
2170 - Liverpool - Liverpool Hospital (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre (1)
6009 - Nedlands - One Clinical Research (1)
2999 - Unspecified - Clinical Trial Site NSW - GenesisCare (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
5112 - Elizabeth Vale - Lyell McEwin Hospital (1)
3144 - Malvern - GenesisCare Cabrini, Cabrini Hospital (1)
4217 - Benowa - Pindara Private Hospital (1)
5042 - Bedford Park - Southern Oncology Clinical Research Unit (1)
Cancer Type
Cancer
Solid tumour
Urogenital cancer
Urothelial carcinoma
Gastrointestinal cancer
Breast cancer
Gynaecological cancer
Cervical cancer
Colorectal cancer
HPV-related cancer
HPV16-positive cancer
Lower gastrointestinal cancer
Upper gastrointestinal cancer
Viral-related cancer
Endometrial cancer
Gastric cancer
Gastroesophageal cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Lung cancer
Non-small cell lung cancer
Oesophageal cancer
Respiratory tract cancer
Thoracic cancer
Breast adenocarcinoma
Gastric carcinoma
Gastroesophageal junction adenocarcinoma
Triple-negative breast cancer
Colorectal adenocarcinoma
Exocrine pancreatic cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pancreatic cancer
Pancreatobiliary cancer
Carcinoma
Clear cell renal cell carcinoma
Hepatobiliary cancer
Hepatocellular carcinoma
Kidney cancer
Neuroendocrine carcinoma
Small-cell lung cancer
Small-cell neuroendocrine carcinoma
Melanoma
Skin cancer
Cutaneous melanoma
Gastrooesophageal adenicarcoma
Microsatellite stable colorectal cancer
Non-microsatellite instability-high colorectal cancer
Male genital cancers
Non-melanoma skin cancer
Oesophageal squamous cell carcinoma
Prostate cancer
Sweat gland carcinoma
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