ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/uveal-melanoma/advanced-metastatic
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
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Melanoma and skin / Uveal Melanoma - Advanced/metastatic
7
trial(s) found.
NCT07203391
Advanced
Phase 1
Recruiting
TRIUMPH
- Tebentafusp and Roginolisib in Uveal Melanoma to Prolong T-cell Homeostasis
PI3K delta inhibitor
bispecfic T-cell engager,gp100-targeting
Uveal melanoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
NCT07070232
Advanced
Phase 1 / Phase 2
Recruiting
A Phase I/II, Open-label, Adaptive Two-part Trial to Evaluate the Safety, Efficacy, Optimal Dose and Pharmacokinetics of BNT326 as Monotherapy and in Combination With Cancer Immunotherapies in Participants With Advanced Solid Tumors (
BNT326-01
)
anti-ERBB3 antibody-drug conjugate
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Gastroesophageal junction adenocarcinoma
Melanoma
Mucosal melanoma
Non-small cell lung cancer
Solid tumour
Uveal melanoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3199 - Frankston - Peninsula Health Frankston Hospital
QLD
4215 - Southport - Tasman Oncology
SA
5000 - Adelaide - Cancer Research SA
WA
6009 - Nedlands - One Clinical Research
NCT07063875
Advanced
Phase 1 / Phase 2
Recruiting
Supplementing With IL-2 to Verifiably eRadicate Radiological Progression (
SILVER
)
Aldesleukin
IL-2 variant
Tebentafusp
bispecfic T-cell engager,gp100-targeting
cancer therapy
cancer therapy,IL-2-targeting
cancer therapy,gp100-targeting
cytokine therapy
cytokine therapy,IL-2-targeting
immuno-oncology therapy,IL-2-targeting
Uveal melanoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
NCT06940739
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2, Open-label Study of a Modified Interleukin-2 Fusion Protein (IOV-3001) in Participants With Previously Treated, Unresectable or Metastatic Melanoma Who Will Receive Lifileucel (
IOV-IL2-101
)
IL-2 fusion protein
autologous tumor-infiltrating lymphocytes therapy
Melanoma
NOT Uveal melanoma
Uveal melanoma
QLD
4120 - Greenslopes - Greenslopes Private Hospital
WA
6009 - Nedlands - Hollywood Private Hospital
NCT06581406
Advanced
Phase 2 / Phase 3
Recruiting
A Randomized, Phase 2/3, Open-Label Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab Versus Ipilimumab in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma (
RP2-202
)
anti-CTLA4 monoclonal antibody
anti-PD-1 monoclonal antibody
bispecific-EGFR/CDH17 antibody-drug conjugate
oncolytic herpes simplex virus
unknown drug class
Uveal melanoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT05549297
Advanced
Phase 3
Recruiting
Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination With Pembrolizumab Versus Investigator's Choice in HLA-A*02:01-positive Participants With Previously Treated Advanced Melanoma (TEBE-AM) (
IMCgp100-203
)
anti-PD-1 monoclonal antibody
bispecfic T-cell engager,gp100-targeting
Melanoma
NOT Uveal melanoma
NSW
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4120 - Greenslopes - Greenslopes Private Hospital
NCT03947385
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions (
IDE196-001
)
PKC inhibitor
Colorectal cancer
Cutaneous melanoma
Solid tumour
Uveal melanoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
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Recruitment Status
Recruiting (7)
Recruitment Country and State
NSW (6)
VIC (5)
QLD (4)
WA (2)
SA (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (4)
Phase 2 / Phase 3 (1)
Phase 3 (1)
Trial Type
Advanced (7)
Cancer Therapy Class
gp100
43%
PD-1/PD-L1
43%
IL-2
29%
PD-1
29%
PI3K delta
14%
ERBB3
14%
PD-L1
14%
SMO
14%
VEGFA
14%
CTLA4
14%
ALK
14%
MEK
14%
MET
14%
PKC
14%
ROS1
14%
Facility
3004 - Melbourne, Southbank - Alfred Health (4)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (3)
2065 - Wollstonecraft - Melanoma Institute Australia - The Poche Centre (3)
4120 - Greenslopes - Greenslopes Private Hospital (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
4215 - Southport - Tasman Oncology (1)
5000 - Adelaide - Cancer Research SA (1)
6009 - Nedlands - One Clinical Research (1)
6009 - Nedlands - Hollywood Private Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
Cancer Type
Cancer
Melanoma
Solid tumour
Uveal melanoma
Colorectal cancer
Gastrointestinal cancer
Lower gastrointestinal cancer
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Lung cancer
Mucosal melanoma
Non-small cell lung cancer
Oesophageal cancer
Respiratory tract cancer
Thoracic cancer
Upper gastrointestinal cancer
Viral-related cancer
Cutaneous melanoma
Skin cancer
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