ARTICANZ - Beta (ver 0.9)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/uveal-melanoma/advanced-metastatic
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
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Melanoma and skin / Uveal Melanoma - Advanced/metastatic
6
trial(s) found.
NCT06007690
Advanced
Phase 3
Recruiting
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma (
CoMpass
)
viral nanoparticle drug conjugates
Choroidal melanoma
Uveal melanoma
VIC
3002 - East Melbourne - Epworth Freemasons
NA
NA
NCT05987332
Advanced
Phase 2 / Phase 3
Recruiting
IDE196 (Darovasertib) in Combination with Crizotinib Versus Investigator's Choice of Treatment As First-line Therapy in HLA-A2 Negative Metastatic Uveal Melanoma (DAR-UM-2) (
IDE196-002
)
ALK inhibitor,first generation
MET inhibitor,type 1
PKC inhibitor
ROS1 inhibitor
Uveal melanoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3181 - Prahran - The Alfred Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5011 - Woodville South - The Queen Elizabeth Hospital
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
NCT05415072
Advanced
Phase 1 / Phase 2
Recruiting
A Phase I/II, Multi-center, Open Label Study of DYP688 in Patients With Metastatic Uveal Melanoma (MUM) and Other GNAQ/11 Mutant Melanomas (
CDYP688A12101
)
GNAQ/GNA11 inhibitor
Uveal melanoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT03947385
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of IDE196 in Patients with Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions (
IDE196-001
)
PKC inhibitor
Colorectal cancer
Cutaneous melanoma
Solid tumour
Uveal melanoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
NCT03746431
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of [225Ac]-FPI-1434 Injection in Patients With Locally Advanced or Metastatic Solid Tumours (
FPX-01-01
)
FPI-1175
FPI-1547
IGF1R-radionucleotide conjugate
cancer therapy
radioconjugate therapy
radiopharmaceutics
Breast cancer
Carcinoma
Cervical cancer
Endometrial cancer
HER2-negative breast cancer
Head and neck squamous cell carcinoma
Ovarian cancer
Solid tumour
Triple-negative breast cancer
Uveal melanoma
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (COMPLETED)
NCT05487235
Advanced
Phase 1
Not recruiting
A Phase Ib, Open-Label Study Evaluating the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors (
GO43712
)
SHP2 inhibitor
anti-PD-L1 monoclonal antibody
Head and neck squamous cell carcinoma
Melanoma
NOT Mucosal melanoma
NOT Uveal melanoma
Non-small cell lung cancer
Solid tumour
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3690 - Wodonga - Border Medical Oncology at Wodonga Regional Cancer Centre
SA
5042 - Bedford Park - Flinders Medical Centre
WA
6009 - Nedlands - One Clinical Research
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
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Recruitment Status
Recruiting (5)
Not recruiting (1)
Recruitment Country and State
VIC (5)
NSW (4)
SA (3)
WA (2)
QLD (1)
NZ (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (3)
Phase 2 / Phase 3 (1)
Phase 3 (1)
Trial Type
Advanced (6)
Cancer Therapy Class
ALK
33%
MET
33%
PD-1/PD-L1
33%
PKC
33%
ROS1
33%
CTLA4
17%
PD-1
17%
GNA11
17%
GNAQ
17%
gp100
17%
MEK
17%
PD-L1
17%
SHP2
17%
Facility
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (3)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (2)
3002 - East Melbourne - Epworth Freemasons (1)
NA
3181 - Prahran - The Alfred Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
3690 - Wodonga - Border Medical Oncology at Wodonga Regional Cancer Centre (1)
5042 - Bedford Park - Flinders Medical Centre (1)
6009 - Nedlands - One Clinical Research (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
Cancer Type
Cancer
Melanoma
Solid tumour
Uveal melanoma
Head and neck cancer
Head and neck squamous cell carcinoma
Choroidal melanoma
Colorectal cancer
Cutaneous melanoma
Gastrointestinal cancer
Lower gastrointestinal cancer
Skin cancer
Breast adenocarcinoma
Breast cancer
Carcinoma
Cervical cancer
Endometrial cancer
Gynaecological cancer
HER2-negative breast cancer
HPV-related cancer
HPV16-positive cancer
Ovarian cancer
Triple-negative breast cancer
Viral-related cancer
Lung cancer
Non-small cell lung cancer
Respiratory tract cancer
Thoracic cancer
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