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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
5
trial(s) found.
NCT06588478
Haem
Phase 2
Recruiting
A Phase 2, Open-Label, Randomized Study Evaluating the Efficacy and Safety of 3 Doses of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Who Previously Received Treatment With a Covalent Bruton Tyrosine Kinase Inhibitor (
2024-515689-15-01--18877
)
BTK inhibitor
Chronic lymphocytic leukaemia
Small lymphocytic lymphoma
NSW
2200 - Bankstown - Bankstown-Lidcombe Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute
VIC
3128 - Box Hill - Box Hill Hospital - Eastern Health
3844 - Traralgon - Latrobe Regional Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5037 - Glandore - Ashford Cancer Centre
5042 - Bedford Park - Flinders Medical Centre
WA
6005 - West Perth - Sir Charles Gairdner Hospital / Western Heamatology and Oncology Clinics
TAS
7000 - Hobart - Royal Hobart Hospital
NCT06120491
Advanced
Phase 3
Recruiting
A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of Saruparib (AZD5305) in Combination With Physician's Choice New Hormonal Agents in Patients With HRRm and Non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01) (
EvoPAR-PR01
)
PARP1-selective inhibitor
placebo
NOT Prostate small cell carcinoma
Prostate cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2031 - Randwick - Prince of Wales Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4032 - Chermside - The Prince Charles Hospital
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4812 - Hyde Park - Icon Cancer Centre Townsville
SA
5037 - Glandore - Ashford Cancer Centre
NCT05536141
Advanced
Phase 1
Recruiting
A Phase 1, Open-label, Dose Escalation and Dose Expansion Study, to Investigate the Safety, Tolerability, and Pharmacokinetic Profile of AB521 Monotherapy and Combination Therapies in Participants With Clear Cell Renal Cell Carcinoma and Other Solid Tumors (
ARC-20
)
HIF2a inhibitor
Clear cell renal cell carcinoma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2109 - North Ryde - Macquarie University Hospital
VIC
3128 - Box Hill - Box Hill Hospital - Eastern Health
SA
5037 - Glandore - Ashford Cancer Centre
NCT05254171
Advanced
Phase 2 / Phase 3
Recruiting
A Randomized, Double-Blind, Placebo-Controlled Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Subjects Previously Untreated for Metastatic Pancreatic Ductal Adenocarcinoma (
ASPIRE
)
antimetabolite
placebo
polyamine analogue
taxane
Pancreatic adenocarcinoma
Pancreatic cancer
NSW
2485 - Tweed Heads - The Tweed Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
SA
5037 - Glandore - Ashford Cancer Centre
WA
6150 - Murdoch - St John of God Murdoch Hospital
NCT04464226
Advanced
Phase 3
Recruiting
An Open-label, Single Arm, Roll-over Study to Provide Continued Treatment With Darolutamide in Participants Who Were Enrolled in Previous Bayer Sponsored Studies
antiandrogen,nonsteroidal,second generation
Cancer
SA
5037 - Glandore - Ashford Cancer Centre
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Recruitment Status
Recruiting (5)
Recruitment Country and State
SA (5)
NSW (4)
VIC (4)
QLD (2)
WA (2)
TAS (1)
ACT (1)
Phase
Phase 1 (1)
Phase 2 (1)
Phase 2 / Phase 3 (1)
Phase 3 (2)
Trial Type
Advanced (4)
Haem (1)
Cancer Therapy Class
AR
40%
androgen axis
40%
BTK
20%
CYP17A1
20%
PARP
20%
PARP1-selective
20%
AXL
20%
CTLA4
20%
HIF2a
20%
KIT
20%
MET
20%
PD-1
20%
PD-1/PD-L1
20%
RET
20%
ROS1
20%
VEGFR
20%
VEGFR2
20%
Facility
5037 - Glandore - Ashford Cancer Centre (5)
3128 - Box Hill - Box Hill Hospital - Eastern Health (2)
2200 - Bankstown - Bankstown-Lidcombe Hospital (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute (1)
3844 - Traralgon - Latrobe Regional Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
5042 - Bedford Park - Flinders Medical Centre (1)
6005 - West Perth - Sir Charles Gairdner Hospital / Western Heamatology and Oncology Clinics (1)
7000 - Hobart - Royal Hobart Hospital (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2031 - Randwick - Prince of Wales Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
4032 - Chermside - The Prince Charles Hospital (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
4812 - Hyde Park - Icon Cancer Centre Townsville (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
2109 - North Ryde - Macquarie University Hospital (1)
2485 - Tweed Heads - The Tweed Hospital (1)
2605 - Garran - The Canberra Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
6150 - Murdoch - St John of God Murdoch Hospital (1)
Cancer Type
Cancer
Solid tumour
Urogenital cancer
B-cell lymphoma
B-cell malignancy
Chronic lymphocytic leukaemia
Haematological malignancy
Leukaemia
Lymphoid leukaemia
Lymphoma
Mature B-cell malignancy
Non-Hodgkin's lymphoma
Small lymphocytic lymphoma
Male genital cancers
Prostate cancer
Clear cell renal cell carcinoma
Kidney cancer
Exocrine pancreatic cancer
Gastrointestinal cancer
Pancreatic adenocarcinoma
Pancreatic cancer
Pancreatobiliary cancer
Upper gastrointestinal cancer
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