ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/BRAF-V600-inhibitor
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/BRAF-V600-inhibitor
3
trial(s) found.
NCT05203172
Advanced
Phase 4
Recruiting
ENCORAFENIB/BINIMETINIB MASTER PROTOCOL: AN OPEN-LABEL CONTINUATION STUDY FOR PARTICIPANTS CONTINUING FROM ENCORAFENIB/BINIMETINIB CLINICAL STUDIES (
C4221026
)
BRAF V600 inhibitor
MEK inhibitor
Solid tumour
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT03975829
Paed
Phase 4
Recruiting
An Open Label, Multi-center Roll-over Study to Assess Long-term Effect in Pediatric Patients Treated With Tafinlar (Dabrafenib) and/or Mekinist (Trametinib) (
CDRB436G2401
)
BRAF V600 inhibitor
MEK inhibitor
Anaplastic astrocytoma
Anaplastic ganglioglioma
Anaplastic oligodendroglioma
Anaplastic pleomorphic xanthoastrocytoma
Astrocytoma
Central neurocytoma
Desmoplastic infantile astrocytoma
Diffuse astrocytoma
Extra-ventricular Neurocytoma
Gangliocytoma
Ganglioglioma
Glioblastoma
Glioma
Liponeurocytoma
Neurofibromatosis
Oligodendroglioma
Papillary glioneuronal tumour
Pilocytic astrocytoma
Pleomorphic xanthoastrocytoma
Rosette-forming glioneuronal tumour
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
VIC
3052 - Parkville - Royal Children's Hospital Melbourne
NCT05182931
Advanced
Phase 2
Unknown
A Prospective, Multi-Centre Trial of TKI Redifferentiation Therapy in Patients With RAIR Thyroid Cancer (
I-FIRST
Study)
BRAF V600 inhibitor
BRAF inhibitor
Dabrafenib
MEK inhibitor
RAF inhibitor
Trametinib
cancer therapy
cancer therapy,BRAF-targeting
cancer therapy,BRAF V600-targeting
cancer therapy,MEK-targeting
cancer therapy,RAF-targeting
+ BRAF V600 inhibitor
NOT Anaplastic thyroid cancer
Thyroid cancer
NSW
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
3181 - Prahran - The Alfred Hospital
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
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Recruitment Status
Recruiting (2)
Unknown (1)
Recruitment Country and State
VIC (3)
NSW (2)
QLD (1)
SA (1)
WA (1)
Phase
Phase 2 (1)
Phase 4 (2)
Trial Type
Advanced (2)
Paed (1)
Cancer Therapy Class
BRAF
100%
BRAF V600
100%
MEK
100%
RAF
100%
CDK4
33%
CDK6
33%
EGFR
33%
Facility
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
3052 - Parkville - Royal Children's Hospital Melbourne (1)
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
3168 - Clayton - Monash Medical Centre (1)
3181 - Prahran - The Alfred Hospital (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
Cancer Type
Cancer
Solid tumour
Anaplastic astrocytoma
Anaplastic ganglioglioma
Anaplastic oligodendroglioma
Anaplastic pleomorphic xanthoastrocytoma
Astrocytoma
Benign glioma
Central nervous system cancer
Central neurocytoma
Desmoplastic infantile astrocytoma
Diffuse astrocytoma
Extra-ventricular Neurocytoma
Gangliocytoma
Ganglioglioma
Glioblastoma
Glioma
Glioneuronal tumour
High-grade glioma
Liponeurocytoma
Low-grade glioma
Malignant glioma
Neuroblastic tumour
Neurofibromatosis
Neurological cancer
Oligodendroglioma
Papillary glioneuronal tumour
Peripheral nervous system tumour
Pilocytic astrocytoma
Pleomorphic xanthoastrocytoma
Rosette-forming glioneuronal tumour
Endocrine gland cancer
Thyroid cancer
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