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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/BTK-PROTAC-degrader
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/BTK-PROTAC-degrader
4
trial(s) found.
NCT06846671
Haem
Phase 3
Recruiting
A Phase 3, Open-Label, Randomized Study of BGB-16673 Compared to Investigator's Choice (Idelalisib Plus Rituximab or Bendamustine Plus Rituximab or Venetoclax Plus Rituximab Retreatment) in Patients With Chronic Lymphocytic Leukemia Previously Exposed to Both BTK and BCL2 Inhibitors (
BGB-16673-302
)
BCL2 inhibitor
BTK PROTAC degrader
PI3K-delta inhibitor
alkylating agent
anti-CD20 monoclonal antibody
Chronic lymphocytic leukaemia
NSW
2139 - Concord - Concord Repatriation General Hospital
2170 - Liverpool - Liverpool Hospital
2560 - Campbelltown - Macarthur Cancer Therapy Centre - Campbelltown Hospital
VIC
3004 - Melbourne, Southbank - Alfred Health
QLD
4350 - Toowoomba - Toowoomba Hospital
WA
6005 - West Perth - Perth Blood Institute
NZ
NZ.0622 - Takapuna - North Shore Hospital
NCT06634589
Haem
Phase 1 / Phase 2
Recruiting
A Phase 1b/2, Open-Label, Master Protocol Study of BTK-Degrader BGB-16673 in Combination With Other Agents in Patients With Relapsed or Refractory B-Cell Malignancies (
BGB-16673-104
)
BTK PROTAC degrader
B-cell lymphoma
B-cell malignancy
Cancer
NSW
2217 - Kogarah - St George Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3004 - Melbourne, Southbank - Alfred Health
3168 - Clayton - Monash Medical Centre
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
WA
6009 - Nedlands - Linear Clinical Research
NZ
NZ.0622 - Takapuna - North Shore Hospital
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NCT05006716
Haem
Phase 1 / Phase 2
Recruiting
A Phase 1/2, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase Targeted Protein Degrader BGB-16673 in Patients With B-Cell Malignancies (
CaDAnCe-101
)
BTK PROTAC degrader
B-cell malignancy
Chronic lymphocytic leukaemia
Diffuse large B-cell lymphoma
Follicular lymphoma
Mantle cell lymphoma
Marginal zone lymphoma
Non-Hodgkin's lymphoma
Small Lymphocytic Lymphoma
Waldenström Macroglobulinemia
NSW
2139 - Concord - Concord Repatriation General Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3004 - Melbourne, Southbank - Alfred Health
3065 - Fitzroy - St Vincent's Hospital Melbourne
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3199 - Frankston - Peninsula Health Frankston Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6005 - West Perth - Perth Blood Institute
6009 - Nedlands - Linear Clinical Research
NCT04861779
Advanced
Phase 1
Unknown
A Phase Ia/b Clinical Study on Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of BTK Protein Degradation Agent HSK29116 in Subjects With Relapsed or Refractory B-Cell Malignancy (
HSK29116-101
)
BTK PROTAC degrader
B-cell malignancy
WA
6009 - Nedlands - One Clinical Research
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Recruitment Status
Recruiting (3)
Unknown (1)
Recruitment Country and State
WA (4)
NSW (3)
QLD (3)
VIC (3)
NZ (2)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 3 (1)
Trial Type
Haem (3)
Advanced (1)
Cancer Therapy Class
BTK
100%
BCL2
50%
CD20
50%
PI3K-delta
25%
Facility
3004 - Melbourne, Southbank - Alfred Health (3)
2139 - Concord - Concord Repatriation General Hospital (2)
6005 - West Perth - Perth Blood Institute (2)
NZ.0622 - Takapuna - North Shore Hospital (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
6009 - Nedlands - Linear Clinical Research (2)
2170 - Liverpool - Liverpool Hospital (1)
2560 - Campbelltown - Macarthur Cancer Therapy Centre - Campbelltown Hospital (1)
4350 - Toowoomba - Toowoomba Hospital (1)
2217 - Kogarah - St George Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
6009 - Nedlands - One Clinical Research (1)
Cancer Type
B-cell malignancy
Cancer
Haematological malignancy
Mature B-cell malignancy
Chronic lymphocytic leukaemia
Leukaemia
Lymphoid leukaemia
B-cell lymphoma
Lymphoma
Non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma
Follicular lymphoma
High-grade B-cell lymphoma
Mantle cell lymphoma
Marginal zone lymphoma
Small Lymphocytic Lymphoma
Waldenström Macroglobulinaemia
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