ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/CCR8
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/CCR8
6
trial(s) found.
NCT07680764
Advanced
Phase 2
Not yet recruiting
A Phase 2, Randomized, Open-label, Study Assessing the Safety, Tolerability and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) (
CA052-1000
)
anti-CCR8 monoclonal antibody
bispecific PD-L1/VEGFA antibody
Non-small cell lung cancer
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
QLD
4120 - Greenslopes - Greenslopes Private Hospital
WA
6150 - Murdoch - Fiona Stanley Hospital
NCT07546812
Advanced
Phase 2
Recruiting
A Phase 2, Open-Label, Multicenter, Randomized Study to Evaluate Denikitug as Monotherapy or in Combination With Nivolumab or Chemotherapy in Participants With HER2-Negative, Unresectable, Recurrent, and/or Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas (
GS-US-742-7757
)
anti-CCR8 monoclonal antibody
anti-PD-1 monoclonal antibody
Gastric adenocarcinoma
Gastric cancer
Gastroesophageal junction adenocarcinoma
cytotoxic chemotherapy
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
WA
6009 - Nedlands - Hollywood Private Hospital
NCT07527858
Advanced
Phase 2
Recruiting
A Phase 2, Open Label, Multicenter, Randomized Study, to Evaluate the Efficacy and Safety of Denikitug Monotherapy and Denikitug-based Combinations in Participants With Advanced Microsatellite Stable (MSS) Colorectal Cancer (CRC) (
GS-US-741-7756
)
anti-CCR8 monoclonal antibody
Microsatellite stable colorectal cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT06819735
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2, Multicentre, Open-label Clinical Trial of DT-7012 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Participants With Selected Advanced Solid Tumors (
DOMISOL
, DOmain_therapeutics Monoclonal antIbody for SOLid Tumors)
anti-CCR8 monoclonal antibody
Solid tumour
NSW
2109 - North Ryde - Macquarie University Hospital
VIC
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
3199 - Frankston - Peninsula Health Frankston Hospital
SA
5000 - Adelaide - Cancer Research SA
WA
6009 - Nedlands - One Clinical Research
NCT05007782
Advanced
Phase 1
Recruiting
A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal Antibody, as Monotherapy and in Combination With an Anti-PD-1 Monoclonal Antibody in Adults With Advanced Solid Tumors (
GS-US-570-6015
)
anti-CCR8 monoclonal antibody
Solid tumour
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3168 - Clayton - Monash Medical Centre
NCT04895709
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors (
CA052-002
)
anti-CCR8 monoclonal antibody
Cervical cancer
Clear cell renal cell carcinoma
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Microsatellite stable colorectal cancer
Non-small cell lung cancer
Ovarian cancer
Pancreatic adenocarcinoma
Triple-negative breast cancer
Urothelial carcinoma
NSW
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
2170 - Liverpool - Liverpool Hospital
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
WA
6009 - Nedlands - One Clinical Research
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Recruitment Status
Recruiting (5)
Not yet recruiting (1)
Recruitment Country and State
NSW (6)
VIC (5)
QLD (4)
WA (4)
SA (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 2 (3)
Trial Type
Advanced (6)
Cancer Therapy Class
CCR8
100%
PD-1/PD-L1
83%
PD-1
67%
PD-L1
33%
VEGFA
33%
VEGFR2
17%
VEGF
17%
Facility
2050 - Camperdown - Chris O'Brien Lifehouse (3)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre (2)
6009 - Nedlands - One Clinical Research (2)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
4120 - Greenslopes - Greenslopes Private Hospital (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
6009 - Nedlands - Hollywood Private Hospital (1)
2109 - North Ryde - Macquarie University Hospital (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
5000 - Adelaide - Cancer Research SA (1)
3168 - Clayton - Monash Medical Centre (1)
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (1)
2170 - Liverpool - Liverpool Hospital (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
Cancer Type
Cancer
Solid tumour
Thoracic cancer
Gastrointestinal cancer
Lung cancer
Non-small cell lung cancer
Respiratory tract cancer
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
Oesophageal cancer
Upper gastrointestinal cancer
Colorectal adenocarcinoma
Colorectal cancer
Lower gastrointestinal cancer
Microsatellite stable colorectal cancer
Non-microsatellite instability-high colorectal cancer
Gastric adenocarcinoma
cytotoxic chemotherapy
Breast adenocarcinoma
Breast cancer
Cervical cancer
Clear cell renal cell carcinoma
Exocrine pancreatic cancer
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Head and neck squamous cell carcinoma
Kidney cancer
Melanoma
Ovarian cancer
Pancreatic adenocarcinoma
Pancreatic cancer
Pancreatobiliary cancer
Triple-negative breast cancer
Urogenital cancer
Urothelial carcinoma
Viral-related cancer
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