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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/CRISPR-Cas9-gene-editing-therapy-TTR-targeting
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Search results
target/CRISPR-Cas9-gene-editing-therapy-TTR-targeting
2
trial(s) found.
NCT06672237
Haem
Phase 3
Recruiting
MAGNITUDE-2: A Phase 3, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) (
ITL-2001-CL-311
)
CRISPR-Cas9 gene-editing therapy,TTR-targeting
placebo
AL amyloidosis
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NCT06128629
Haem
Phase 3
Recruiting
MAGNITUDE: a Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants with Transthyretin Amyloidosis with Cardiomyopathy (ATTR-CM) (
ITL-2001-CL-301
)
CRISPR-Cas9 gene-editing therapy,TTR-targeting
placebo
Solid tumour
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3004 - Melbourne, Southbank - Alfred Health
3128 - Box Hill - Box Hill Hospital - Eastern Health
QLD
4870 - Cairns - Cairns Base Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre
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Recruitment Status
Recruiting (2)
Recruitment Country and State
NSW (2)
NZ (2)
ACT (1)
QLD (1)
SA (1)
VIC (1)
WA (1)
Phase
Phase 3 (2)
Trial Type
Haem (2)
Cancer Therapy Class
TTR
100%
Facility
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (2)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (2)
2605 - Garran - The Canberra Hospital (1)
3004 - Melbourne, Southbank - Alfred Health (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
4870 - Cairns - Cairns Base Hospital (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre (1)
Cancer Type
Cancer
AL amyloidosis
Amyloidosis
Haematological malignancy
Plasma cell disorder
Solid tumour
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