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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/CYP11A1-inhibitor
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/CYP11A1-inhibitor
2
trial(s) found.
NCT06353386
Advanced
Phase 1 / Phase 2
Recruiting
MK-
5684-01A
Substudy: A Phase 1/2 Umbrella Substudy of MK-5684-U01 Master Protocol to Evaluate the Safety and Efficacy of MK-5684-based Treatment Combinations or MK-5684 Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)
CYP11A1 inhibitor
Castrate-resistant prostate cancer
NSW
2109 - North Ryde - Macquarie University Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4120 - Greenslopes - Greenslopes Private Hospital
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NCT06136650
Advanced
Phase 3
Recruiting
MK-
5684-004
: A Phase 3, Randomized, Open-label Study of Opevesostat Versus Alternative Abiraterone Acetate or Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment With One Next-generation Hormonal Agent (NHA) (OMAHA-004)
CYP11A1 inhibitor
CYP17A1 inhibitor
antiandrogen,nonsteroidal,second generation
Castrate-resistant prostate cancer
Prostate cancer
NSW
2109 - North Ryde - Macquarie University Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3168 - Clayton - Monash Medical Centre
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.9016 - Dunedin - Dunedin Hospital (COMPLETED)
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Recruitment Status
Recruiting (2)
Recruitment Country and State
NSW (2)
NZ (2)
QLD (2)
VIC (2)
Phase
Phase 1 / Phase 2 (1)
Phase 3 (1)
Trial Type
Advanced (2)
Cancer Therapy Class
CYP11A1
100%
androgen axis
100%
PARP
50%
AR
50%
CYP17A1
50%
Facility
2109 - North Ryde - Macquarie University Hospital (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (2)
4120 - Greenslopes - Greenslopes Private Hospital (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
NZ.9016 - Dunedin - Dunedin Hospital (1)
Cancer Type
Cancer
Castrate-resistant prostate cancer
Male genital cancers
Prostate adenocarcinoma
Prostate cancer
Solid tumour
Urogenital cancer
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