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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/DNA-minor-groove-binding-agent
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Search results
target/DNA-minor-groove-binding-agent
3
trial(s) found.
NCT07625644
Advanced
Phase 3
Recruiting
A Phase 3 Open-Label, Randomized Controlled Trial of BL-M14D1 and Atezolizumab vs. Standard-of-Care Therapy in Patients With First-Line Extensive-Stage Small Cell Lung Cancer (
BL-M14D1-LC-301
)
anti-DLL3 antibody-drug conjugate,topoisomerase inhibitor 1-payload
anti-PD-L1 monoclonal antibody
+ DNA minor groove-binding agent
Lung cancer
Small-cell lung cancer
Small-cell neuroendocrine carcinoma
ACT
2605 - Garran - The Canberra Hospital
QLD
4215 - Southport - Tasman Oncology
SA
5042 - Bedford Park - Flinders Medical Centre
NCT06801834
Advanced
Phase 3
Recruiting
A Global, Multicenter, Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Standard of Care (SOC) in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer (ES-SCLC) (
EVOKE-SCLC-04
)
anti-Trop2 antibody-drug conjugate
+ DNA minor groove-binding agent
Small-cell lung cancer
NSW
2500 - Wollongong - Cancer Care Wollongong
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4215 - Southport - Gold Coast University Hospital
SA
5000 - Adelaide - Cancer Research SA
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
NCT06203210
Advanced
Phase 3
Recruiting
A Phase 3, Multicenter, Randomized, Open-label Study of Ifinatamab Deruxtecan (I-DXd), a B7-H3 Antibody Drug Conjugate (ADC), Versus Treatment of Physician's Choice (TPC) in Subjects With Relapsed Small Cell Lung Cancer (SCLC) (
IDeate-Lung02
)
anti-B7H3 antibody-drug conjugate,topoisomerase inhibitor 1-payload
+ DNA minor groove-binding agent
Small-cell lung cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3021 - St Albans - Western Health - Sunshine Hospital
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital
SA
5042 - Bedford Park - Flinders Medical Centre
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
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Recruitment Status
Recruiting (3)
Recruitment Country and State
QLD (3)
SA (3)
NSW (2)
VIC (2)
WA (2)
ACT (1)
Phase
Phase 3 (3)
Trial Type
Advanced (3)
Cancer Therapy Class
PD-1/PD-L1
33%
PD-L1
33%
Trop2
33%
B7H3
33%
Facility
5042 - Bedford Park - Flinders Medical Centre (2)
2605 - Garran - The Canberra Hospital (1)
4215 - Southport - Tasman Oncology (1)
2500 - Wollongong - Cancer Care Wollongong (1)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
4215 - Southport - Gold Coast University Hospital (1)
5000 - Adelaide - Cancer Research SA (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital (1)
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital (1)
Cancer Type
Cancer
Carcinoma
Lung cancer
Neuroendocrine carcinoma
Respiratory tract cancer
Small-cell lung cancer
Small-cell neuroendocrine carcinoma
Solid tumour
Thoracic cancer
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