ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/EGFR-inhibitor-fourth-generation
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/EGFR-inhibitor-fourth-generation
4
trial(s) found.
NCT07699328
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of VRN110755 in Patients With Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC) (
REACH-EGFR
)
EGFR inhibitor,fourth generation
EGFR-mutant non-small cell lung cancer
VIC
3168 - Clayton - Monash Medical Centre
SA
5042 - Bedford Park - Southern Oncology Clinical Research Unit
NCT06905197
Advanced
Phase 1
Recruiting
A Phase 1, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD6008 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations (TIAN-SHAN1) (
DZ2023C0001
)
EGFR inhibitor,fourth generation
Non-small cell lung cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
NCT06760819
Advanced
Phase 2
Recruiting
A Phase 2 Open-label Basket Study to Evaluate the Efficacy and Safety of Orally Administered Reversible Tyrosine Kinase Inhibitor BAY 2927088 in Participants With Metastatic or Unresectable Solid Tumors With HER2-activating Mutations (
panSOHO
)
EGFR/ERBB2 inhibitor,mutant-selective,non-covalent
+ EGFR inhibitor,fourth generation
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Endometrial cancer
NOT Biliary tract cancer
NOT Colorectal cancer
NOT Non-small cell lung cancer
NOT Urothelial carcinoma
Urothelial carcinoma
NSW
2109 - North Ryde - Macquarie University Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
QLD
4215 - Southport - ICON Cancer Care
NCT06452277
Advanced
Phase 3
Recruiting
A Phase 3 Open-label, Randomized, Active-controlled, Multicenter Trial to Evaluate the Efficacy and Safety of Orally Administered BAY 2927088 Compared With Standard of Care as a First-line Therapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With HER2-activating Mutations (
SOHO-02
)
EGFR/ERBB2 inhibitor,mutant-selective,non-covalent
+ EGFR inhibitor,fourth generation
Non-small cell lung cancer
NSW
2139 - Concord - Concord Repatriation General Hospital
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
ACT
2605 - Garran - The Canberra Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
QLD
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic
4350 - Toowoomba - Toowoomba Hospital (WITHDRAWN)
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Recruitment Status
Recruiting (4)
Recruitment Country and State
NSW (3)
VIC (2)
QLD (2)
SA (1)
ACT (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (1)
Phase 2 (1)
Phase 3 (1)
Trial Type
Advanced (4)
Cancer Therapy Class
EGFR
100%
ERBB2
75%
PD-1
25%
PD-1/PD-L1
25%
Facility
2148 - Blacktown - Blacktown Hospital, Blacktown Cancer and Haematology Centre (3)
3168 - Clayton - Monash Medical Centre (1)
5042 - Bedford Park - Southern Oncology Clinical Research Unit (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
2109 - North Ryde - Macquarie University Hospital (1)
4215 - Southport - ICON Cancer Care (1)
2139 - Concord - Concord Repatriation General Hospital (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2605 - Garran - The Canberra Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
4350 - Toowoomba - Toowoomba Hospital (1)
4556 - Buderim - Sunshine Coast Haematology and Oncology Clinic (1)
Cancer Type
Cancer
Solid tumour
Lung cancer
Non-small cell lung cancer
Respiratory tract cancer
Thoracic cancer
EGFR-mutant non-small cell lung cancer
Breast cancer
Cervical cancer
Colorectal adenocarcinoma
Colorectal cancer
Endometrial cancer
Gastrointestinal cancer
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Lower gastrointestinal cancer
Urogenital cancer
Urothelial carcinoma
Viral-related cancer
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