ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/HDAC
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/HDAC
4
trial(s) found.
NCT07244705
Advanced
Phase 1 / Phase 2
Recruiting
An Open-label, Multicenter, Phase 1/2 Study Exploring the Safety and Efficacy of ABT-301 in Combination With Tislelizumab and Bevacizumab in Participants With Proficient Mismatch Repair (pMMR)/Non-Microsatellite Instability-High (Non-MSI-H) Locally Advanced or Metastatic Colorectal Cancer (mCRC) (
ABT-301-103
)
HDAC inhibitor
anti-PD-1 monoclonal antibody
anti-VEGF monoclonal antibody
Colorectal adenocarcinoma
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
2170 - Liverpool - Liverpool Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
QLD
4120 - Greenslopes - Greenslopes Private Hospital
SA
5011 - Woodville South - The Queen Elizabeth Hospital
WA
6009 - Nedlands - Linear Clinical Research
NCT06561048
Haem
Phase 3
Recruiting
A Phase 3, Randomized, Open-Label Study to Investigate the Efficacy and Safety of ITK Inhibitor Soquelitinib Versus Physician's Choice Standard of Care Treatment (Selected Single Agent) in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma (
CPI-818-004
)
ITK inhibitor
+ HDAC inhibitor
Anaplastic large cell lymphoma
Angioimmunoblastic T-cell lymphoma
Lymphoma
Peripheral T-cell lymphoma
T-cell lymphoma
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2217 - Kogarah - St George Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3121 - Richmond - Epworth Freemasons Hospital
3128 - Box Hill - Box Hill Hospital - Eastern Health
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5042 - Bedford Park - Flinders Medical Centre
WA
6009 - Nedlands - Linear Clinical Research
TAS
7000 - Hobart - Royal Hobart Hospital
NCT03838042
Paed
Phase 1 / Phase 2
Recruiting
INFORM2 Exploratory Multinational Phase I/II Combination Study of Nivolumab and Entinostat in Children and Adolescents With Refractory High-risk Malignancies (INFORM2-NivEnt) (
Final4,-18-10-2023
)
HDAC inhibitor,class 1 selective
anti-PD-1 monoclonal antibody
Central nervous system cancer
Solid tumour
NSW
2031 - Randwick - Sydney Children's Hospital
2145 - Westmead - The Children's Hospital at Westmead
VIC
3052 - Parkville - Royal Children's Hospital Melbourne
WA
6009 - Perth - Perth Children's Hospital
ACTRN12616001021460
Curative
Phase 1
Not yet recruiting
A Phase I trial of Sodium Valproate/MetformIn Combination as neoadjuvant therapy for ProstatE canceR (
VIPER-1-trial
)
HDAC inhibitor
biguanide antihyperglycaemic agent
Prostate cancer
SA
5042 - Bedford Park - Flinders Medical Centre
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Recruitment Status
Recruiting (3)
Not yet recruiting (1)
Recruitment Country and State
NSW (3)
SA (3)
VIC (3)
WA (3)
QLD (2)
TAS (1)
Phase
Phase 1 (1)
Phase 1 / Phase 2 (2)
Phase 3 (1)
Trial Type
Advanced (1)
Haem (1)
Paed (1)
Curative (1)
Cancer Therapy Class
HDAC
100%
PD-1
50%
PD-1/PD-L1
50%
VEGF
25%
DHFR
25%
ITK
25%
Facility
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (2)
6009 - Nedlands - Linear Clinical Research (2)
5042 - Bedford Park - Flinders Medical Centre (2)
2031 - Randwick - Scientia Clinical Research Ltd (1)
2109 - North Ryde - Macquarie University Hospital (1)
2170 - Liverpool - Liverpool Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4120 - Greenslopes - Greenslopes Private Hospital (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2217 - Kogarah - St George Hospital (1)
3121 - Richmond - Epworth Freemasons Hospital (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
7000 - Hobart - Royal Hobart Hospital (1)
2031 - Randwick - Sydney Children's Hospital (1)
2145 - Westmead - The Children's Hospital at Westmead (1)
3052 - Parkville - Royal Children's Hospital Melbourne (1)
6009 - Perth - Perth Children's Hospital (1)
Cancer Type
Cancer
Solid tumour
Colorectal adenocarcinoma
Colorectal cancer
Gastrointestinal cancer
Lower gastrointestinal cancer
Anaplastic large cell lymphoma
Angioimmunoblastic T-cell lymphoma
Haematological malignancy
Lymphoma
Non-Hodgkin's lymphoma
Peripheral T-cell lymphoma
T-cell lymphoma
Central nervous system cancer
Neurological cancer
Male genital cancers
Prostate cancer
Urogenital cancer
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