ARTICANZ - Beta (ver 0.9)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/IL-2
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/IL-2
5
trial(s) found.
NCT06108479
Advanced
Phase 1
Recruiting
A Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in Combination Therapy in Patients with Advanced (Unresectable, Recurrent, or Metastatic) Solid Tumors (
DF6215-001
)
IL-2 variant
Cancer
Solid tumour
VIC
3199 - Frankston - PASO Medical
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT05267626
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2, First-in-Human, Open Label, Dose Escalation and Expansion Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer (
CP-AU-007-01
)
anti-IL-2 monoclonal antibody
Cancer
Solid tumour
NSW
2228 - Miranda - Southside Cancer Care Centre
VIC
3004 - Melbourne, Southbank - Alfred Health
3021 - St Albans - Western Health - Sunshine Hospital
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
3199 - Frankston - Peninsula Health Frankston Hospital
SA
5042 - Bedford Park - Southern Oncology Clinical Research Unit
NCT05086692
Advanced
Phase 1 / Phase 2
Recruiting
A Phase 1/2 Open Label, Dose Escalation and Expansion Study of MDNA11, IL-2 Superkine, Administered Alone or in Combination With Immune Checkpoint Inhibitor in Patients With Advanced Solid Tumors (
ABILITY-1
)
IL-2 superkine
Acral lentiginous melanoma
Bladder cancer
Cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous melanoma
Cutaneous squamous cell carcinoma
Endometrial carcinoma
Epithelial Ovarian Cancer
Fallopian tube cancer
Gastric cancer
Gastroesophageal junction adenocarcinoma
Head and neck squamous cell carcinoma
Melanoma
Merkel cell carcinoma
Mucosal melanoma
Non-melanoma skin cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pleural mesothelioma
Primary peritoneal serous carcinoma
Skin cancer
Solid tumour
Squamous non-small-cell lung cancer
Triple-negative breast cancer
dMMR solid cancer
NSW
2031 - Randwick - Scientia Clinical Research Ltd
2109 - North Ryde - Macquarie University Hospital
QLD
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation
NCT04830124
Advanced
Phase 2
Recruiting
A Phase 2, Open-Label, Multicenter, Cohort Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous Melanoma or Advanced Mucosal Melanoma -
ARTISTRY-6
IL-2 fusion protein
anti-PD-1 monoclonal antibody
Cutaneous melanoma
Mucosal melanoma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
QLD
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital
SA
5011 - Woodville South - The Queen Elizabeth Hospital
ACTRN12623001217695
Advanced
Phase 1
Not yet recruiting
An Open-Label Dose-Escalation Phase Ia Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Efficacy of IMD-101 Injectable in Participants with Advanced Malignant Solid Tumours.
IL2 conjugate
Solid tumour
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Recruitment Status
Recruiting (4)
Not yet recruiting (1)
Recruitment Country and State
SA (3)
NSW (3)
VIC (2)
QLD (2)
Phase
Phase 1 (2)
Phase 1 / Phase 2 (2)
Phase 2 (1)
Trial Type
Advanced (5)
Cancer Therapy Class
IL-2
100%
PD-1
80%
PD-1/PD-L1
80%
PD-L1
20%
Facility
3199 - Frankston - PASO Medical (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
2228 - Miranda - Southside Cancer Care Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3168 - Clayton - Monash Medical Centre (1)
3199 - Frankston - Peninsula Health Frankston Hospital (1)
5042 - Bedford Park - Southern Oncology Clinical Research Unit (1)
2031 - Randwick - Scientia Clinical Research Ltd (1)
2109 - North Ryde - Macquarie University Hospital (1)
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital (1)
5011 - Woodville South - The Queen Elizabeth Hospital (1)
Cancer Type
Cancer
Solid tumour
Cutaneous melanoma
Melanoma
Mucosal melanoma
Skin cancer
Acral lentiginous melanoma
Biomarker-defined solid tumour
Bladder cancer
Breast adenocarcinoma
Breast cancer
Cervical cancer
Clear cell renal cell carcinoma
Colorectal cancer
Cutaneous basal cell carcinoma
Cutaneous squamous cell carcinoma
Endometrial cancer
Endometrial carcinoma
Epithelial Ovarian Cancer
Exocrine pancreatic cancer
Fallopian tube cancer
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
Gastrointestinal cancer
Gynaecological cancer
HPV-related cancer
HPV16-positive cancer
Head and neck cancer
Head and neck squamous cell carcinoma
High-grade serous carcinoma of the ovary, fallopian tube, and peritoneum
Kidney cancer
Lower gastrointestinal cancer
Lung cancer
MSI-H/dMMR solid tumour
Merkel cell carcinoma
Mesothelioma
Non-melanoma skin cancer
Non-small cell lung cancer
Non-squamous non-small-cell lung cancer
Oesophageal cancer
Ovarian cancer
Pancreatic adenocarcinoma
Pancreatic cancer
Pancreatobiliary cancer
Peritoneal cancer
Pleural mesothelioma
Primary peritoneal serous carcinoma
Respiratory tract cancer
Squamous non-small-cell lung cancer
Thoracic cancer
Triple-negative breast cancer
Upper gastrointestinal cancer
Urogenital cancer
Viral-related cancer
dMMR solid cancer
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