ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/JAK
Home
By cancer type
By drug class
By site
Data
FAQ
About
⚠
ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/JAK
7
trial(s) found.
NCT07623161
Haem
Phase 3
Recruiting
A Phase 3, Double-Blind, Randomized Trial Evaluating the Efficacy and Safety of Elritercept (TAK-226) Compared to Placebo in Participants With Myelofibrosis and Anemia on Concurrent Ruxolitinib Therapy (
ELRISE-MF
)
JAK1/JAK2 inhibitor
modified ActRIIA ligand trap protein
placebo
Myelofibrosis
NSW
2217 - Kogarah - St George Hospital
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute
2487 - Cudgen - Tweed Valley Hospital
SA
5042 - Bedford Park - Flinders Medical Centre
NCT07357727
Haem
Phase 3
Recruiting
A Phase 3, Randomized, Double-blind, Active-control Study of Pelabresib (DAK539) and Ruxolitinib vs. Placebo and Ruxolitinib in Adult Patients With Myelofibrosis Who Are JAK Inhibitor Naive (
MANIFEST-3
)
BET inhibitor
JAK1/JAK2 inhibitor
placebo
Essential thrombocythaemia
Myelofibrosis
Polycythaemia vera
VIC
3168 - Clayton - Monash Medical Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT06479135
Haem
Phase 3
Recruiting
A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in JAK Inhibitor-Na\xEFve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib (
POIESIS
)
JAK1/JAK2 inhibitor
MDM2 inhibitor
placebo
Myelofibrosis
NSW
2217 - Kogarah - St George Hospital
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3004 - Melbourne, Southbank - Alfred Health
3168 - Clayton - Monash Medical Centre
QLD
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6000 - Perth - Royal Perth Hospital
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - Royal Hobart Hospital
NCT05269771
Paed
No longer available
Treatment Plan for Managed Access Program (MAP) to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera (PV) (
CINC424B2002I
)
JAK1/JAK2 inhibitor
Polycythemia vera
NSW
2800 - Orange - Orange Hospital-Cancer Centre Clinical Trials Unit
NCT05037760
Haem
Phase 2
Recruiting
A Phase 2 Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of KER-050 as Monotherapy or in Combination With Ruxolitinib in Participants With Myelofibrosis (
KER050-MF-301
)
JAK1/JAK2 inhibitor
modified ActRIIA ligand trap protein
Myelofibrosis
NSW
2139 - Concord - Concord Repatriation General Hospital
2485 - Tweed Heads - The Tweed Hospital
VIC
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health
3065 - Fitzroy - St Vincent's Hospital Melbourne
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit
SA
5042 - Bedford Park - Flinders Medical Centre
NCT04176198
Haem
Phase 1 / Phase 2
Recruiting
A Phase 1/2, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral Nuvisertib (TP-3654) in Patients With Intermediate or High-Risk Primary or Secondary Myelofibrosis (
BBI-TP-3654-102
)
PIM1 kinase inhibitor,selective
+ JAK1/JAK2 inhibitor
Myelofibrosis
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3065 - Fitzroy - St Vincent's Hospital Melbourne
3121 - Richmond - Epworth Freemasons Hospital
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5037 - Kurralta Park - Icon Cancer Centre Adelaide
ACTRN12619001298101
Advanced
Phase 2
Not yet recruiting
A Phase IIa Study to assess the Efficacy and Safety of ASN-002 alone and in combination with chemotherapy in adult participants with Low-Risk Basal Cell Carcinomas (
ASN-002-IL
)
SYK/JAK inhibitor
Cutaneous basal cell carcinoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
Additional search terms:
API and Webpage URLs:
Copy /Bookmark
Filters
Recruitment Status
Recruiting (5)
No longer available (1)
Not yet recruiting (1)
Recruitment Country and State
SA (5)
NSW (4)
VIC (4)
QLD (2)
TAS (1)
WA (1)
Phase
Phase 1 / Phase 2 (1)
Phase 2 (2)
Phase 3 (3)
Trial Type
Haem (5)
Paed (1)
Advanced (1)
Cancer Therapy Class
JAK1
86%
JAK2
86%
BET
14%
MDM2
14%
JAK
14%
SYK
14%
Facility
3168 - Clayton - Monash Medical Centre (3)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (3)
2217 - Kogarah - St George Hospital (2)
5042 - Bedford Park - Flinders Medical Centre (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (2)
3065 - Fitzroy - St Vincent's Hospital Melbourne (2)
2450 - Coffs Harbour - Coffs Harbour Health Campus - The North Coast Cancer Institute (1)
2487 - Cudgen - Tweed Valley Hospital (1)
2250 - Gosford - Central Coast Cancer Centre, Gosford Hospital (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
3004 - Melbourne, Southbank - Alfred Health (1)
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital (1)
6000 - Perth - Royal Perth Hospital (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
7000 - Hobart - Royal Hobart Hospital (1)
2800 - Orange - Orange Hospital-Cancer Centre Clinical Trials Unit (1)
2139 - Concord - Concord Repatriation General Hospital (1)
2485 - Tweed Heads - The Tweed Hospital (1)
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health (1)
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit (1)
3121 - Richmond - Epworth Freemasons Hospital (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
5037 - Kurralta Park - Icon Cancer Centre Adelaide (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
Cancer Type
Cancer
Haematological malignancy
Myeloproliferative neoplasm
Myelofibrosis
Polycythaemia vera
Essential thrombocythaemia
Cutaneous basal cell carcinoma
Non-melanoma skin cancer
Skin cancer
Solid tumour
URLs for this search
API URL:
Copy
Bookmarkable URL:
Copy