ARTICANZ - Beta (ver 0.9)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/RANK-L
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/RANK-L
3
trial(s) found.
ACTRN12624000588594
Advanced
Phase 2
Not yet recruiting
A Phase 2, Open-Label, Multicentre Study to Assess the Preliminary Efficacy and Safety of RXC004, in Patients with Advanced Pancreatic Cancer that have Progressed following Therapy with Current Standard of Care (
PORCUPINE2-Australian-Extension
)
PORCN inhibitor
+ anti-RANK L monoclonal antibody
Pancreatic cancer
ACTRN12618001121257
Advanced
Phase 1 / Phase 2
Recruiting
Pharmacodynamics of Pre-Operative PD1 Checkpoint Blockade and Receptor Activator of NFkB Ligand (RANKL) Inhibition in Non-Small Cell Lung Cancer (NSCLC) - a phase 1B/2 trial (
POPCORN
)
Denosumab
Nivolumab
anti-PD-1 monoclonal antibody
anti-RANK L monoclonal antibody
cancer therapy
cancer therapy,PD-1-targeting
cancer therapy,PD-1/PD-L1-targeting
cancer therapy,RANK L-targeting
immune checkpoint blockade
immune checkpoint blockade,PD-1-targeting
immuno-oncology therapy,PD-1-targeting
immuno-oncology therapy,RANK L-targeting
+ anti-RANK L monoclonal antibody
Non-small cell lung cancer
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4032 - Chermside - The Prince Charles Hospital
4102 - Woolloongabba - Princess Alexandra Hospital
NCT03280667
Advanced
Phase 2
Unknown
Denosumab and Pembrolizumab in Clear Cell Renal Carcinoma: a Phase II Trial (ANZUP 1601) (
KEYPAD
)
anti-PD-1 monoclonal antibody
anti-RANK L monoclonal antibody
Clear cell renal cell carcinoma
Kidney cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2086 - Frenchs Forest - Northern Beaches Hospital
2139 - Concord - Concord Repatriation General Hospital
2217 - Kogarah - St George Hospital
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
2640 - Albury - Border Medical Oncology Research Unit
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3128 - Box Hill - Box Hill Hospital - Eastern Health
3168 - Clayton - Monash Medical Centre
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4575 - Birtinya - Sunshine Coast University Hospital
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital
SA
5042 - Bedford Park - Flinders Medical Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
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Recruitment Status
Not yet recruiting (1)
Recruiting (1)
Unknown (1)
Recruitment Country and State
QLD (2)
NSW (1)
SA (1)
VIC (1)
WA (1)
Phase
Phase 1 / Phase 2 (1)
Phase 2 (2)
Trial Type
Advanced (3)
Cancer Therapy Class
RANK L
100%
PD-1
67%
PD-1/PD-L1
67%
PORCN
33%
Facility
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (2)
4032 - Chermside - The Prince Charles Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2086 - Frenchs Forest - Northern Beaches Hospital (1)
2139 - Concord - Concord Repatriation General Hospital (1)
2217 - Kogarah - St George Hospital (1)
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (1)
2640 - Albury - Border Medical Oncology Research Unit (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3128 - Box Hill - Box Hill Hospital - Eastern Health (1)
3168 - Clayton - Monash Medical Centre (1)
3355 - Wendouree - Ballarat Oncology & Haematology Clinical Trials Unit (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
4575 - Birtinya - Sunshine Coast University Hospital (1)
4814 - Douglas - Townsville Cancer Centre - The Townsville Hospital (1)
5042 - Bedford Park - Flinders Medical Centre (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
Cancer Type
Cancer
Solid tumour
Gastrointestinal cancer
Pancreatic cancer
Pancreatobiliary cancer
Upper gastrointestinal cancer
Lung cancer
Non-small cell lung cancer
Respiratory tract cancer
Thoracic cancer
Clear cell renal cell carcinoma
Kidney cancer
Urogenital cancer
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