ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/TTR
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/TTR
4
trial(s) found.
NCT07223203
Haem
Phase 3
Recruiting
TRITON-PN
: A Phase 3, Global, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy (hATTR-PN)
siRNA therapy,TTR-targeting
AL amyloidosis
Amyloidosis
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
NCT07052903
Haem
Phase 3
Recruiting
TRITON-CM: A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Transthyretin-Mediated Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy) (
ALN-TTRSC04-003
)
placebo
siRNA therapy,TTR-targeting
Transthyretin Amyloidosis
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2170 - Liverpool - Liverpool Hospital
VIC
3128 - Box Hill - Box Hill Hospital - Eastern Health
QLD
4032 - Chermside - The Prince Charles Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5042 - Bedford Park - Flinders Medical Centre
WA
6027 - Joondalup - Joondalup Health Campus
NZ
NZ.2025 - Papatoetoe - Aotearoa Clinical Trials - Middlemore Hospital
NZ.3210 - Hamilton - Waikato Hospital
NZ.8011 - Christchurch - New Zealand Clinical Research
NCT06672237
Haem
Phase 3
Recruiting
MAGNITUDE-2: A Phase 3, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) (
ITL-2001-CL-311
)
CRISPR-Cas9 gene-editing therapy,TTR-targeting
placebo
AL amyloidosis
NCT06128629
Haem
Phase 3
Recruiting
MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) (
ITL-2001-CL-301
)
CRISPR-Cas9 gene-editing therapy,TTR-targeting
placebo
Solid tumour
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3004 - Melbourne, Southbank - Alfred Health
3128 - Box Hill - Box Hill Hospital - Eastern Health
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
4870 - Cairns - Cairns Base Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre
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Recruitment Status
Recruiting (4)
Recruitment Country and State
NSW (3)
QLD (3)
NZ (2)
SA (2)
VIC (2)
WA (2)
ACT (1)
Phase
Phase 3 (4)
Trial Type
Haem (4)
Cancer Therapy Class
TTR
50%
Facility
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (2)
3128 - Box Hill - Box Hill Hospital - Eastern Health (2)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (2)
2170 - Liverpool - Liverpool Hospital (1)
4032 - Chermside - The Prince Charles Hospital (1)
5042 - Bedford Park - Flinders Medical Centre (1)
6027 - Joondalup - Joondalup Health Campus (1)
NZ.2025 - Papatoetoe - Aotearoa Clinical Trials - Middlemore Hospital (1)
NZ.3210 - Hamilton - Waikato Hospital (1)
NZ.8011 - Christchurch - New Zealand Clinical Research (1)
2605 - Garran - The Canberra Hospital (1)
3004 - Melbourne, Southbank - Alfred Health (1)
4870 - Cairns - Cairns Base Hospital (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre (1)
Cancer Type
Cancer
Amyloidosis
Haematological malignancy
Plasma cell disorder
AL amyloidosis
Transthyretin Amyloidosis
Solid tumour
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