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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/anti-CLDN18.2-monoclonal-antibody
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Search results
target/anti-CLDN18.2-monoclonal-antibody
2
trial(s) found.
NCT07431281
Advanced
Phase 3
Recruiting
A Phase III, Multicentre, Randomised Controlled Study of Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in First-Line Claudin18.2-Positive, HER2-Negative, Advanced/Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (CLARITY-Gastric 02) (
D9803C00001
)
anti-CLDN18.2 antibody-drug conjugate
bispecific PD-1/TIGIT antibody
fluoropyrimidine
+ anti-CLDN18.2 monoclonal antibody
Gastric cancer
Gastroesophageal junction adenocarcinoma
Oesophageal cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
2031 - Randwick - Prince of Wales Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
ACT
2605 - Garran - The Canberra Hospital
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
NCT06901531
Advanced
Phase 3
Recruiting
A Phase 3, Double-blind, Randomized Study of Zolbetuximab in Combination With Pembrolizumab and Chemotherapy (CAPOX or mFOLFOX6) in First-line Treatment of Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma in Participants Whose Tumors Are HER2-negative, Claudin (CLDN) 18.2-positive and Programmed Death-ligand 1 (PD-L1)-Positive (
LUCERNA
)
anti-CLDN18.2 monoclonal antibody
anti-PD-1 monoclonal antibody
Gastroesophageal junction adenocarcinoma
VIC
3168 - Clayton - Monash Medical Centre
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
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Recruitment Status
Recruiting (2)
Recruitment Country and State
VIC (2)
ACT (1)
NSW (1)
WA (1)
QLD (1)
Phase
Phase 3 (2)
Trial Type
Advanced (2)
Cancer Therapy Class
CLDN18.2
100%
PD-1
100%
PD-1/PD-L1
100%
TIGIT
50%
Facility
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (1)
2031 - Randwick - Prince of Wales Hospital (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
2605 - Garran - The Canberra Hospital (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
3168 - Clayton - Monash Medical Centre (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
Cancer Type
Cancer
Gastric cancer
Gastric carcinoma
Gastroesophageal cancer
Gastroesophageal junction adenocarcinoma
Gastrointestinal cancer
Oesophageal cancer
Solid tumour
Thoracic cancer
Upper gastrointestinal cancer
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