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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/autologous-CAR-T-cell-therapy-CD19-targeting
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/autologous-CAR-T-cell-therapy-CD19-targeting
6
trial(s) found.
NCT06528301
Haem
Phase 1
Recruiting
A Phase 1, Multicenter, Open-label Study of UB-VV111 in Combination With Rapamycin in Relapsed/Refractory (R/R) CD19+ B-cell Malignancies (
UB-VV111-01
)
gene therapy,CAR-T-cell generating,CD19-targeting
+ autologous CAR-T-cell therapy,CD19-targeting
Chronic lymphocytic leukaemia
Diffuse large B-cell lymphoma
Lymphoma
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
NCT06486051
Haem
Phase 2
Recruiting
A Phase 2 Trial to Evaluate the Efficacy and Safety of WZTL-002 in Patients With Relapsed or Refractory Large B-cell Lymphoma (
ENABLE-2
)
CAR-T-cell therapy
CAR-T-cell therapy,CD19-targeting
Cyclophosphamide
Fludarabine
WZTL002
alkylating agent
antimetabolite
autologous CAR-T-cell therapy
autologous CAR-T-cell therapy,CD19-targeting
cancer therapy
cancer therapy,CD19-targeting
cell therapy
cytotoxic chemotherapy
+ autologous CAR-T-cell therapy,CD19-targeting
Diffuse large B-cell lymphoma
Non-Hodgkin's lymphoma
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.6021 - Wellington - Capital & Coast District Health Board - Wellington Hospital
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre
NCT06079164
Haem
Phase 1
Recruiting
A Phase 1 Open-label, Single Arm, Multicenter Study Evaluating the Safety and Efficacy of KITE-197 in Subjects With Relapsed or Refractory Large B-cell Lymphoma (
KT-US-656-0601
)
autologous CAR-T-cell therapy,CD19-targeting
Diffuse large B-cell lymphoma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3004 - Melbourne, Southbank - Alfred Health
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT05605899
Haem
Phase 3
Recruiting
An Adaptive Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Axicabtagene Ciloleucel Versus Standard of Care Therapy as First-Line Therapy in Subjects With High-Risk Large B-Cell Lymphoma (
ZUMA-23
)
autologous CAR-T-cell therapy,CD19-targeting
Diffuse large B-cell lymphoma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
NCT03601442
Haem
Available
Managed Access Program (MAP) Cohort Treatment Plan
CCTL019B2003I
to Provide Access for Patients With Out of Specification Leukapheresis Product and/or Out of Specification Manufactured Tisagenlecleucel (CTL019; Kymriah®)
autologous CAR-T-cell therapy,CD19-targeting
Acute lymphoblastic leukaemia
Diffuse large B-cell lymphoma
WA
6150 - Murdoch - Fiona Stanley Hospital (AVAILABLE)
ACTRN12621000762853
Haem
Phase 1
Recruiting
Phase I Clinical Trial of MB.CART19.1 CD19 Chimeric Antigen Receptor (CAR) T Cells in Relapsed or Refractory CD19-Positive Haematological Malignancy
autologous CAR-T-cell therapy,CD19-targeting
B-cell malignancy
Leukaemia
Non-Hodgkin's lymphoma
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
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Recruitment Status
Recruiting (5)
Recruitment Country and State
VIC (3)
QLD (3)
NSW (2)
NZ (1)
Phase
Phase 1 (3)
Phase 2 (1)
Phase 3 (1)
Trial Type
Haem (6)
Cancer Therapy Class
CD19
100%
mTOR
17%
mTORC1
17%
mTORC2
17%
CD20
17%
Facility
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (3)
2050 - Camperdown - Chris O'Brien Lifehouse (2)
3065 - Fitzroy - St Vincent's Hospital Melbourne (1)
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (1)
NZ.6021 - Wellington - Capital & Coast District Health Board - Wellington Hospital (1)
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
Cancer Type
B-cell malignancy
Cancer
Haematological malignancy
Lymphoma
Non-Hodgkin's lymphoma
B-cell lymphoma
Diffuse large B-cell lymphoma
High-grade B-cell lymphoma
Mature B-cell malignancy
Leukaemia
Lymphoid leukaemia
Chronic lymphocytic leukaemia
Acute lymphoblastic leukaemia
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