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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/bispecific-T-cell-engager-FcRH5-targeting
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/bispecific-T-cell-engager-FcRH5-targeting
4
trial(s) found.
NCT05927571
Haem
Phase 1
Recruiting
An Open-Label, Multicenter, Phase Ib Trial Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Patients With Relapsed or Refractory Multiple Myeloma (
GO43979
)
bispecific T-cell engager,BCMA-targeting
bispecific T-cell engager,FcRH5-targeting
Multiple myeloma
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3181 - Prahran - The Alfred Hospital
NCT05583617
Haem
Phase 1 / Phase 2
Recruiting
A Platform Study Evaluating the Safety and Efficacy of Multiple Treatments in Patients With Multiple Myeloma (
PLYCOM
)
CELMoD agent
Cevostamab
Dexamethasone
Iberdomide
Lenalidomide
Tocilizumab
anti-IL-6 monoclonal antibody
bispecific T-cell engager,FcRH5-targeting
cancer therapy
cancer therapy,FcRH5-targeting
cancer therapy,IL-6-targeting
cancer therapy,cereblon-targeting
cereblon modulator
glucocorticoid
immuno-oncology therapy,FcRH5-targeting
immuno-oncology therapy,IL-6-targeting
immunomodulatory imide drug
therapeutic modality,bispecific T-cell engager
therapeutic modality,bispecific antibody
+ bispecific T-cell engager,FcRH5-targeting
Multiple myeloma
NSW
2031 - Randwick - Prince of Wales Hospital
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
NCT05646836
Haem
Phase 1
Active not recruiting
A Phase Ib, Open-label, Multicenter Dose-escalation Study to Evaluate the Safety, Pharmacokinetics, and Activity of XmAb24306 in Combination With Cevostamab in Patients With Relapsed/Refractory Multiple Myeloma (
GO43980
)
IL-15/IL-15R Fc-fusion protein
bispecific T-cell engager,FcRH5-targeting
Multiple myeloma
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3004 - Melbourne, Southbank - Alfred Health
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT05535244
Haem
Phase 1 / Phase 2
Active not recruiting
A Phase I/II, Open-Label, Multi-Cohort Study to Evaluate the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen-Exposed Patients With Relapsed/Refractory Multiple Myeloma (
CAMMA-2
)
bispecific T-cell engager,FcRH5-targeting
Multiple myeloma
NSW
2298 - Waratah - Calvary Mater Newcastle Medical Oncology
VIC
3065 - Fitzroy - St Vincent's Hospital Melbourne
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Recruitment Status
Recruiting (2)
Active not recruiting (2)
Recruitment Country and State
VIC (4)
NSW (3)
SA (1)
Phase
Phase 1 (2)
Phase 1 / Phase 2 (2)
Trial Type
Haem (4)
Cancer Therapy Class
FcRH5
100%
IL-6
100%
BCMA
25%
cereblon
25%
IL-15
25%
Facility
2298 - Waratah - Calvary Mater Newcastle Medical Oncology (2)
3065 - Fitzroy - St Vincent's Hospital Melbourne (2)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
3181 - Prahran - The Alfred Hospital (1)
2031 - Randwick - Prince of Wales Hospital (1)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3004 - Melbourne, Southbank - Alfred Health (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
Cancer Type
Cancer
Haematological malignancy
Multiple myeloma
Plasma cell disorder
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