ARTICANZ - Beta (ver 0.91)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/radioconjugate-PSMA-targeting
Home
By cancer type
By drug class
By site
Data
FAQ
About
⚠
ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/radioconjugate-PSMA-targeting
12
trial(s) found.
NCT07226986
Radonc
Phase 1 / Phase 2
Recruiting
A Phase Ib/II Open-label, Multi-center Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With an Androgen Receptor Pathway Inhibitor (ARPI) in Adult Participants With PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) (
CAMO959A12103
)
DNA-dependent protein kinase inhibitor
radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
VIC
3004 - Melbourne, Southbank - Alfred Health
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
WA
6150 - Murdoch - Fiona Stanley Hospital
NCT07090369
Radonc
Phase 1
Not yet recruiting
Phase Ib Trial of 177Lu-PSMA-I&T Therapy in Combination With Olaparib and Pembrolizumab in Patients With Metastatic Castration Resistant Prostate Cancer (
LumOnate
)
PARP1/2 inhibitor
anti-PD-1 monoclonal antibody
radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT06855277
Radonc
Phase 3
Recruiting
A Phase III, Open-label, Multi-center, Randomized Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive Metastatic Castration Resistant Prostate Cancer (
AcTFirst
)
radioligand,PSMA-targeting
+ radioconjugate,PSMA-targeting
Prostate cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT06520345
Radonc
Phase 3
Recruiting
A Multinational, Multicenter, Prospective, Randomized, Controlled, Open-Label, Phase 3 Study of Lutetium (177Lu) Rosopatamab Tetraxetan in Combination With Standard of Care Versus Standard of Care Alone in Patients With PSMA Positive Metastatic Castration-Resistant Prostate Cancer Previously After Androgen Receptor Pathway Inhibitor Treatment (
177Lu-TLX591-203
)
radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
Prostate cancer
NSW
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2305 - New Lambton Heights - Hunter New England Cancer Centre - John Hunter Hospital
2500 - Wollongong - Wollongong Hospital
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre
VIC
3051 - Melbourne - Australian Prostate Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3144 - Malvern - GenesisCare Cabrini, Cabrini Hospital
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital
WA
6150 - Murdoch - GenesisCare Murdoch
NA
NA
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre
NCT06095089
Advanced
Phase 1
Recruiting
A Phase 1 Study of JNJ-87189401 (PSMA-CD28 Bispecific Antibody) Combined With JNJ-78278343 (KLK2-CD3 Bispecific Antibody) for Advanced Prostate Cancer (
CR109330
)
bispecific T-cell engager,KLK2-targeting
+ radioconjugate,PSMA-targeting
Prostate cancer
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
NCT05939414
Radonc
Phase 3
Recruiting
An International, Prospective, Open-label, Multi-center, Randomized Phase III Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) Versus Observation to Delay Castration or Disease Recurrence in Adult Male Patients With Prostate-specific Membrane Antigen (PSMA) Positive Oligometastatic Prostate Cancer (OMPC) (
PSMA-DC
)
radioconjugate,PSMA-targeting
Prostate cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
VIC
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre
QLD
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
NCT05818683
Advanced
Phase 1
Recruiting
A Phase 1b Study of JNJ-78278343, Targeting Human Kallikrein 2 (KLK2) in Combination With Other Agents for Metastatic Prostate Cancer (
CR109321
)
bispecific T-cell engager,KLK2-targeting
+ radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
Castrate-sensitive prostate cancer
NSW
2109 - North Ryde - Macquarie University Hospital
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
QLD
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5037 - Kurralta Park - Icon Cancer Centre Adelaide
ACTRN12625000971437
Radonc
Phase 2
Recruiting
Dose Optimisation and PSMA Receptor intensification with 177Lu-PSMA Therapy in Patients Diagnosed with Metastatic Castrate Resistant Prostate Cancer : A Randomised Phase II trial:
OPTIMAL-PSMA
radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
NSW
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre
ACTRN12623001072606
Radonc
Phase 1
Recruiting
A phase 1a/b dose-escalation and dose-expansion study to evaluate Lutetium-177-PSMA I&T (Lu-PSMA) with radiosensitising Capecitabine in patients with metastatic castration-resistant prostate cancer (mCRPC) (
LuCape
)
fluoropyrimidine
radioconjugate,PSMA-targeting
Castrate-resistant prostate cancer
WA
6150 - Murdoch - Fiona Stanley Hospital
ACTRN12623000216617
Radonc
Phase 1
Not yet recruiting
A pilot, feasibility study of 177Lu-DOTA-Rosopatamab (TLX591) therapy in castrate resistant prostate adenocarcinoma patients showing progression on radioligand therapy using PSMA small molecule ligands (
RESCUE
)
radioligand,PSMA-targeting
+ radioconjugate,PSMA-targeting
Prostate cancer
NA
NA
NZ
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research
ACTRN12623000073606
Radonc
Phase 0
Not yet recruiting
A Single-Arm, Open-Label, Prospective, Phase 0 Trial Evaluating the Safety and Efficacy of Salvage 177Lu-PSMA-I&T in Prostate Specific Antigen (PSA) Biochemical Failure After Radical Prostatectomy for High-Risk Prostate Cancer (
SLAP-trial
)
radioconjugate,PSMA-targeting
Prostate cancer
NSW
2076 - Wahroonga - Sydney Adventist Hospital
ACTRN12618001667202
Radonc
Phase 3
Not yet recruiting
A Randomised Trial of External Beam Radiation Therapy (EBRT) Alone versus EBRT in Combination with 177Lu-PSMA Theranostic in Patients with Biochemically Recurrent Prostate Cancer (to determine the proportion of participants in each group with a 50% decline in PSA through to the end of the trial) - a phase 3 study (
TARGET
)
radioconjugate,PSMA-targeting
radiotherapy
Prostate cancer
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
Additional search terms:
API and Webpage URLs:
Copy /Bookmark
Filters
Recruitment Status
Recruiting (8)
Not yet recruiting (4)
Recruitment Country and State
VIC (6)
NSW (6)
WA (4)
SA (3)
QLD (3)
NZ (2)
Phase
Phase 0 (1)
Phase 1 (5)
Phase 1 / Phase 2 (1)
Phase 2 (1)
Phase 3 (4)
Trial Type
Radonc (10)
Advanced (2)
Cancer Therapy Class
PSMA
100%
AR
42%
androgen axis
42%
CYP17A1
33%
PD-1
17%
PD-1/PD-L1
17%
KLK2
17%
DNA-dependent protein kinase
8%
PARP
8%
Facility
3000 - Melbourne - Peter MacCallum Cancer Centre (3)
2010 - Darlinghurst - St Vincent's Hospital Sydney - The Kinghorn Cancer Centre (3)
3144 - Malvern - Cabrini Health, Cabrini Cancer Care Centre (2)
6150 - Murdoch - Fiona Stanley Hospital (2)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (2)
NA
NZ.1023 - Grafton - Auckland City Hospital - Cancer & Blood Research (2)
3004 - Melbourne, Southbank - Alfred Health (1)
2065 - St Leonards - Northern Sydney Cancer Centre, Royal North Shore Hospital (1)
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (1)
2305 - New Lambton Heights - Hunter New England Cancer Centre - John Hunter Hospital (1)
2500 - Wollongong - Wollongong Hospital (1)
2747 - Kingswood - Nepean Hospital - Nepean Cancer Care Centre (1)
3051 - Melbourne - Australian Prostate Centre (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3144 - Malvern - GenesisCare Cabrini, Cabrini Hospital (1)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
4224 - Tugun - Genesis Care Tugun - John Flynn Private Hospital (1)
6150 - Murdoch - GenesisCare Murdoch (1)
NZ.8011 - Christchurch - Canterbury District Health Board - Christchurch Hospital Cancer Centre (1)
4006 - Herston - The Royal Brisbane and Women's Hospital Cancer Centre (1)
2109 - North Ryde - Macquarie University Hospital (1)
4102 - Woolloongabba - Princess Alexandra Hospital (1)
5037 - Kurralta Park - Icon Cancer Centre Adelaide (1)
2076 - Wahroonga - Sydney Adventist Hospital (1)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (1)
Cancer Type
Cancer
Male genital cancers
Prostate cancer
Solid tumour
Urogenital cancer
Castrate-resistant prostate cancer
Prostate adenocarcinoma
Castrate-sensitive prostate cancer
URLs for this search
API URL:
Copy
Bookmarkable URL:
Copy