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Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - target/thymidine-phosphorylase-inhibitor
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
target/thymidine-phosphorylase-inhibitor
4
trial(s) found.
NCT06614192
Advanced
Phase 3
Not recruiting
AndroMETa-CRC-064: An Open Label, Randomized, Controlled, Global Phase 3 Study Comparing ABBV-400 Monotherapy to LONSURF (Trifluridine and Tipiracil) Plus Bevacizumab in Subjects With c-Met Over-Expressed Refractory Metastatic Colorectal Cancer (
M24-064
)
Tipiracil Hydrochloride
Trifluridine
anti-VEGF monoclonal antibody
anti-cMET antibody-drug conjugate
antimetabolite
thymidine phosphorylase inhibitor
Colorectal cancer
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
NCT05328908
Advanced
Phase 3
Active not recruiting
A Phase 3, Randomized, Open-label Study of Relatlimab-nivolumab Fixed-dose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants With Later-lines of Metastatic Colorectal Cancer (
RELATIVITY-123
)
KIT/PDGFR/RET/VEGFR/FGFR inhibitor
Tipiracil Hydrochloride
Trifluridine
anti-LAG3 monoclonal antibody
anti-PD-1 monoclonal antibody
antimetabolite
thymidine phosphorylase inhibitor
Colorectal adenocarcinoma
NSW
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
2650 - Wagga Wagga - Riverina Cancer Care Centre
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
QLD
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation
WA
6150 - Murdoch - Fiona Stanley Hospital
NCT05198934
Advanced
Phase 3
Active not recruiting
A Phase 3 Multicenter, Randomized, Open-label, Active-controlled Study of Sotorasib and Panitumumab Versus Investigator's Choice (Trifluridine and Tipiracil, or Regorafenib) for the Treatment of Previously Treated Metastatic Colorectal Cancer Subjects With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation (
CodeBreak300
)
KIT/PDGFR/RET/VEGFR/FGFR inhibitor
KRAS G12C/NRAS G12C/HRAS G12C inhibitor
anti-EGFR monoclonal antibody
+ thymidine phosphorylase inhibitor
Colorectal cancer
NSW
2050 - Camperdown - Chris O'Brien Lifehouse
2065 - St Leonards - GenesisCare North Shore Private Hospital
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital
SA
5011 - Woodville South - The Queen Elizabeth Hospital
ACTRN12617001190392
Advanced
Phase 1 / Phase 2
Status unknown
An open label phase IB/II, non-randomised, dose-finding, safety and tolerability study of Panitumumab, Irinotecan, Trifluridine/Tipiracil in RAS wild-type patients with metastatic colorectal cancer (
PIT-Study
)
Tipiracil Hydrochloride
Trifluridine
anti-EGFR monoclonal antibody
antimetabolite
thymidine phosphorylase inhibitor
topoisomerase inhibitor
Colorectal cancer
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
5011 - Woodville South - The Queen Elizabeth Hospital
5042 - Bedford Park - Flinders Medical Centre
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Recruitment Status
Active not recruiting (2)
Not recruiting (1)
Status unknown (1)
Recruitment Country and State
QLD (2)
NSW (2)
SA (2)
VIC (1)
WA (1)
Phase
Phase 1 / Phase 2 (1)
Phase 3 (3)
Trial Type
Advanced (4)
Cancer Therapy Class
FGFR
50%
FGFR1
50%
FGFR1/2/3
50%
FGFR2
50%
FGFR3
50%
FGFR4
50%
KIT
50%
PDGFR
50%
RET
50%
VEGFR
50%
EGFR
50%
MET
25%
VEGF
25%
LAG3
25%
PD-1
25%
PD-1/PD-L1
25%
HRAS G12C
25%
KRAS
25%
KRAS G12C
25%
NRAS G12C
25%
Facility
2145 - Westmead - The Crown Princess Mary Cancer Centre - Westmead Hospital (2)
5011 - Woodville South - The Queen Elizabeth Hospital (2)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (1)
2650 - Wagga Wagga - Riverina Cancer Care Centre (1)
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (1)
3168 - Clayton - Monash Medical Centre (1)
4120 - Greenslopes - Greenslopes Private Hospital- Gallipoli Medical Research Foundation (1)
6150 - Murdoch - Fiona Stanley Hospital (1)
2050 - Camperdown - Chris O'Brien Lifehouse (1)
2065 - St Leonards - GenesisCare North Shore Private Hospital (1)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (1)
5042 - Bedford Park - Flinders Medical Centre (1)
Cancer Type
Cancer
Colorectal cancer
Gastrointestinal cancer
Lower gastrointestinal cancer
Solid tumour
Colorectal adenocarcinoma
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